Transferrin saturation is reported as a percentage of transferrin that is saturated with iron. Serum iron levels and total iron binding capacity (TIBC) are two tests done on the blood, and their results are used to calculate this value. A serum iron level in the range of 60-170 micrograms/...
Serum transferrin saturation increase is associated with decrease of antibacterial activity of serum in patients with HFE-related genetic hemochromatosis. 来自 EBSCO 喜欢 0 阅读量: 48 作者: A Jolivet-Gougeon,O Loréal,A Ingels,B Danic,M Ropert,E Bardou-Jacquet,N Aqodad,F Aussant-Bertel,C ...
Transferrin saturation (TSAT) is a reliable marker of iron status. According to National Kidney Foundation - Dialysis Outcomes Quality Initiative (NKF-DOQI) guidelines, a TSAT < 20% indicates iron deficiency, whereas a TSAT > 50% may indicate iron overload in hemodialysis (HD) patients.1'2...
In both types of anemia, transferrin saturation values drop below 20%11. Anemia has been extensively studied in the context of TB and both iron deficiency-related and chronic disease-associated anemias have been reported12,13,14,15. The specific interplay between systemic inflammation, mycobacterial...
Transferrin is present in the blood in different iron-bound forms: devoid of iron (apotransferrin, ATf), as monoferric Tf, or as diferric Tf (holotransferrin, HTf). The relative amount of iron-free and iron-loaded Tf in blood is given in terms of the % Tf saturation (TSAT), an ...
Transferrin saturation was elevated in 7/13 (53.8%) male individuals and 5/14 (35.7%) female individuals (w2¼0.90, P¼0.34). Only one male individual (320 mg/l) and one female individual (261 mg/l) had raised serum ferritin, and in both cases, it was only marginally raised above...
in one-week intervals. Blood tests were carried out every 60 min for five hours. NTBI detection was performed using the fluorescein-labeled apotransferrin method. Plasma iron values were highly increased after 65 mg NaFeEDTA, twice as high as after FeSO4. A similar pattern was seen for NTBI....
Here, we found that mice with an intestinal ferritin H gene deletion show increased body iron stores and transferrin saturation. As expected for iron-loaded animals, the ferritin H-deleted mice showed induced liver hepcidin mRNA levels and reduced duodenal expression of DMT1 and DcytB mRNA. In ...
Full blood count to exclude anemia, serum ferritin and transferrin saturation, serum urea and creatinine and blood glucose should be performed, at a minimum. With symptoms or physical findings suggestive of nerve root damage or neuropathy, the patient should be evaluated for neuropathy and for ...
In cultures performed in serum-free conditions, IMDM was supplemented with 1.5% bovine serum albumin (BSA; Cohn's fraction V; Sigma), sonicated lipids, and iron-saturated human transferrin.32 Cultures were performed in three conditions, ie, absence of any cytokine, presence of PEG-rhuMGDF (10...