Transferrin saturation (TSAT) is a reliable marker of iron status. According to National Kidney Foundation - Dialysis Outcomes Quality Initiative (NKF-DOQI) guidelines, a TSAT < 20% indicates iron deficiency, whereas a TSAT > 50% may indicate iron overload in hemodialysis (HD) patients.1'2...
Transferrin saturation is reported as a percentage of transferrin that is saturated with iron. Serum iron levels and total iron binding capacity (TIBC) are two tests done on the blood, and their results are used to calculate this value. A serum iron level in the range of 60-170 micrograms/...
Transferrin saturation can be calculated by using the serum iron concentration and one of the following: total iron binding capacity, unsaturated iron binding capacity, or transferrin level. The serum iron concentration, although often elevated in hemochromatosis, has been a less reliable test than ...
Studies were carried out in rats to evaluate the release of iron from monoferric and diferric transferrin. Isoelectric focusing was carried out on plasma tagged at low and high saturations, and it was shown that these represented primarily monoferric and diferric transferrin, respectively. In vivo...
The serum iron concentration usually is elevated, and the transferrin saturation of iron is increased. La concentración sérica de hierro suele estar elevada y lo mismo sucede con la saturación de hierro de la transferrina. Literature Transferrin Transferrina tmClass In preparing the compoun...
The other mechanism involves low affinity, non-specific and non-saturable internalization of transferrin-bound iron, probably through pinocytosis, adsorptive endocytosis or low affinity binding sites. At low transferrin saturation, the first mechanism is quantitatively most important, at high transferrin ...
Iron accumulation and iron balance dysregulation are observed in animal models of retinal degeneration. Recently, we observed iron overload in ocular fluids from retinal detachment patients and highly transferrin saturation. As therapeutic strategy, we used transferrin (TF), the physiological iron ...
Levels of serum iron, total iron binding capacity, transferrin saturation fraction and packed cell volume of blood donors in Calabar, Cross River State, Nigeria. Pakistan J Nutri. 2008; 7 :500–2.Akpotuzor J, Isong C, Okpokam O, Etukudo M. Levels of serum iron, total iron binding ...
SERUM IRON CONCENTRATION (SI) AND TRANSFERRIN SATURATION (SAT) ARE LOWER IN NORMAL CHILDREN THAN IN ADULTSPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology...
Transferrin Saturation (TS) TS is usually reported along with the serum iron (SI) and total iron binding capacity (TIBC). TS indicates the percent of iron binding sites on transferrin that are carrying iron. TS is derived from a calculation using the formula: ...