Background & aims: Iron overload is known to cause diabetes. However, the underlying mechanism is poorly understood. We therefore studied the association of different markers of iron metabolism, namely ferritin, erythrocyte protoporphyrin and transferrin saturation (TSAT, as defined by a.percentage ...
% saturation and ferritin.And the TIBC, an indirect measure of the iron-carrying protein transferrin, will be lower in the range when all three of the former are too high
At 12 months, transferrin saturation index and GTN-induced vasodilation returned to values similar to those at baseline in both groups of subjects. CONCLUSIONS: Iron depletion improves vascular dysfunction in type 2 diabetic patients with high ferritin concentrations. The mechanisms by which these ...
High affinity iron uptake in Saccharomyces cerevisiae requires a metal reductase, a multicopper ferroxidase, and an iron permease. Fet3, the apparent ferroxidase, is proposed to facilitate iron uptake by catalyzing the oxidation of reductase-generated Fe(II) to Fe(III) by O2; in this model, Fe...
Diagnosis of iron-deficiency anemia in the elderly purpose: To determine the value of serum ferritin, mean cell volume, transferrin saturation, and free erythrocyte protoporphyrin in the diagnosis of iron-d... GH Guyatt,C Patterson,M Ali,... - 《American Journal of Medicine》 被引量: 717发表...
twenty-eight YY individuals had iron indices assessed, following the identification of their genetic status (Supplementary Table 1). Transferrin saturation was elevated in 7/13 (53.8%) male individuals and 5/14 (35.7%) female individuals (w2¼0.90, P¼0.34). Only one male individual (320 ...
correlated with serum transferrin saturation (Spearman test,r = 0.78,p < 0.001) and, by trend, with serum iron (r = 0.69,p = 0.004). Nigral echogenicity was not clearly related to serum values associated with iron metabolism. Susceptibility and echogenicity measurements were ...
Transferrin saturation (TfSat) was calculated using the formula [S-Iron (mol/L) ϫ 0.038]/S- Transferrin (g/L)*100 and the TfR-F Index was defined as TfR/ LogFerritin. In case of suspected birth asphyxia, blood was drawn into 1 mL syringe and analyzed immediately using Rapidlab ...
Serum iron, total iron binding capacity, transferrin saturation index, and HLA typing were determined by standard techniques as previously reported.35 Serum Ft was measured by an enzyme immunoassay. Hepatic iron stores were evaluated and graded microscopically (0-4) by two independent observers and ...
(7.32%), hematocrit (Hct) (8.02%), plasmairon (PI) (7.65%), transferrin saturation (TS) (9.65%) decreased consistently in majority of respondents and Ca (4.91%), Total-Iron-Binding-Capacity (TIBC) (2.26%), Unsaturated- Iron-Binding-Capacity (UIBC) (7.48%), MDA (30.1%) and SOD (...