An enzyme called protein kinase C is another interior peripheral membrane protein. It initiates signaling pathways inside the cell. Peripheral membrane proteins do not interact with the non-polar region of the cell membrane. Instead, they are bound to the cell membrane through interactions between ...
Because reverse translocation of PKCs is dependent on their kinase activity (20), reaccumulation of PKCα in the cytoplasm following DiC8 treatment is indicative of enzyme activation. To confirm that this is the case in IEC-18 cells, the effect of the PKC inhibitor bisindolylmaleimide I was inv...
Because this kinase family is absent from mammalian hosts, it represents a validated target that may be exploitable for chemotherapy against T. gondii and related apicomplexans. 展开 关键词: Protozoa Apicomplexa Toxoplasma gondii Defensive secretion Enzyme Calcium Pathogenic Parasite Exocytosis Protozoa ...
The metalloendopeptidase EC (EP24.15) is a neuropeptide-metabolizing enzyme expressed predominantly in brain, pituitary, and testis, and is implicated in several physiological processes and diseases. Multiple putative phosphorylation sites in the primary sequence led us to investigate whether phosphorylation ...
Increased mycobacterial growth and decreased lipid bodies in protein kinase-Cδ (PKCδ)-deficient macrophages. (a) Expression of PKCδ and other isoforms in bone marrow-derived macrophages (BMDMs) infected with an HN878 strain of Mycobacterium tuberculosis (Mtb) from CAGE study. (b) PKCδ mRNA...
Replicase enzyme (RNA polymerase) is an enzyme used in RNA-dependent RNA synthesis, a process that enables the formation RNA strand complementary to a...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough...
www.nature.com/scientificreports OPEN received: 22 September 2016 accepted: 12 December 2016 Published: 18 January 2017 Protein kinase C δ signaling is required for dietary prebiotic- induced strengthening of intestinal epithelial barrier function Richard Y. Wu1,2, Majd Abdullah1, Pekka ...
DNA-dependent protein kinase (DNA-PK) is essential for activation of DNA ligase I in sulfur mustard (SM)-exposed cultured normal human epidermal keratinocytes (NHEK) 来自 mendeley.com 喜欢 0 阅读量: 10 作者:KR Bhat,BJ Benton,R Ray
The NAD(+) kinase (NADK) is the only known enzyme capable of phosphorylating NAD(H) to NADP(H) and therefore it plays a crucial role in maintaining NAD(P)(H) homeostasis. All domains of life contain at least one NADK gene, and the commonly investigated isoforms have been measured, or ...
We had previously shown that the majority of protein kinase C-δ (PKC-δ) produced in insect cells was inactive; less than 1% of the expressed enzyme had lipid-dependent kinase activity. In this report, we have attempted to optimize the production of a catalytically active PKC-δ. Under ...