When is iron overload deleterious, and when and how should iron chelation therapy be administered in myelodysplastic syndromes? Best Pract. Res. Clin. Haematol. 2013; 26: 431-444.Steensma DP, Gattermann N. When is iron overload deleterious, and when and how should iron chelation therapy be ...
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Much less widely known than the dangerous consequences of iron deficiencies is the fact that too much iron can also cause problems. The exact origin of the genetic iron overload disorder hereditary hemochromatosis (HH) has remained elusive. In a joint effort, researchers from the European Molecular...
Iron-overload cardiomyopathy is a prevalent cause of heart failure on a world-wide basis and is a major cause of mortality and morbidity in patients with secondary iron-overload and genetic hemochromatosis. We investigated the therapeutic effects of resv
High RPE iron levels have been associated with age-related macular degeneration. Mutation of the ferroxidase ceruloplasmin leads to RPE iron accumulation and degeneration in patients with aceruloplasminemia; mice lacking ceruloplasmin and its homolog hephaestin have a similar RPE degeneration. To determin...
Hereditary hemochromatosis is an iron overload disorder and is the most common recessive disease in Caucasians. About 80% of hemochromatosis patients are h... OT Njajou,BZ Alizadeh,CMV Duijn - 《European Journal of Epidemiology》 被引量: 185发表: 2004年 Making the Most of an Internship: An ...
While rusted iron being unattractive to look at is a downside to iron cookware, it can also be very dangerous to your health. When rust and bacteria come into contact, an open cut you may have on your hand becomes more susceptible to infection. Tetanus, a potentially fatal illness, can ...
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Mutations of the HFE were detected in a substantial proportion of donors and pts 2)HFE was always of donor origin after SCT 3)The majority of surviving pts after SCT have markedly increased body iron stores correlating with the no.of BT 4)There seems to be a correlation between iron stores...