Areas covered: Iron chelation therapy (ICT) can help remove excess iron and ultimately reduce the clinical consequences of iron overload. The authors reviewed recent (last five years) English-language articles from PubMed on the topic of iron overload-related complications and the use of ICT (...
Disruption in iron homoeostasis can cause iron deficiency and iron overload. Iron deficiency affects over two billion people worldwide1, which underscores the need to understand its long-term consequences on population health. Although iron overload is less prevalent, its extreme form—hemochromatosis...
II. Prevalence of iron deficiency and iron overload on 1319 women aged 40–70 years. Influence of blood donation, alcohol intake, and iron supplementation. Ann Hematol 79:612–621 Article PubMed CAS Google Scholar Milman N, Clausen J, Byg K-E (1998) Iron status in 268 Danish women ...
Deficiency as well as overload of iron cause symptoms of disease.Iron deficiency causes anaemia,and is especially dangerous for children and pregnant women. Iron overload causes liver cirrhosis,diabetes,cardiomyopathy,arthropathy,increased succeptibility to infections,and probably carcinoma.In Germany the...
Copper is an essential co-factor of key metabolic enzymes that participate in a variety of physiological processes, including respiration, neurotransmitter biosynthesis, radical detoxification, and iron uptake.1, 2 However, excess copper must be promptly exported from the cell because accumulated metal ...
Histologic Features of the Liver in Insulin Resistance–Associated Iron Overload The aim of the present study was to describe histologic features of the liver in insulin resistance鈥揳ssociated hepatic iron overload (IR-HIO), defined as... Bruno,Turlin,Michel,... - 《American Journal of Cli...
Copper: Effects of Deficiency and Overload Chapter© 2013 Background Copper is a generally utilized heavy metal [1] with a toxic limit beyond 10 μM [2,3]. At low concentrations, copper ion is an essential micronutrient that plays a variety of functions in biological systems. Copper contain...
2018). Here, we provide a simplified overview of the neural consequences when the HPA axis is chronically activated, resulting in an allostatic overload that is generally associated with poorer physical and mental health outcomes (Guidi et al. 2021). Environmental stresses cause three, cascading ...
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs) J. Clin. Invest., 117 (2007), pp. 1926-1932 View in ScopusGoogle Scholar [128] L. Poellinger, R.S. Johnson HIF-1 and hypoxic response: the plot thickens Curr. Opin. Genet. Dev., 14 (2004), pp. ...
The performance of the balance and thus the minimum weight can vary over time because of changing e nvironmental conditions. 2. Different operators may weigh differently on the balance – i.e., the minimum weight determined by different operators may be different. 3. The standard ...