aFinal adjudication and coding of histology, hormone receptor status (positive or negative), and ERBB2 (HER2) status (overexpression or not) based on pathology report review was performed at the WHI Clinical Coordinating Center using the Surveillance, Epidemiology, and End Results coding system. 组织...
Parsley is a good dietary source of apigenin, which has been shown to exhibit potent growth-inhibitory effects in HER2+ breast cancer cells. Apigenin has also been shown to inhibit the growth of patient-derived triple negative (ER-/PR-/HER2-) organoids and sensitize triple negative cells to ...
Celery flavone apigenin has been found to induce apoptosis across a variety of breast cancer cell lines. For example, apigenin has been shown to exhibit potent growth-inhibitory effects inHER2+breast cancer cells. Exposure of HER2+ breast cancer cells to apigenin results in induction of apoptosis ...
Rody A, Holtrich U, Pusztai L, Liedtke C, Gaetje R, Ruckhaeberle E, Solbach C, Hanker L, Ahr A, Metzler D, Engels K, Karn T, Kaufmann M (2009) T- cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers. Breast Cancer Res 11: ...
As of 11/15/2020, 1,973 customers were included in the AGMT-MBC-Registry. Out of 1,729 evaluable clients, 351 (20.3%) had been HER2-positive, 608 (35.2%) had been HER2-low and 770 (44.5%) were completely HER2-negative (HER2-0). Minimal HER2-expression had been markedly more regul...
This is a post hoc analysis of information from MONARCH 2, a stage III research of abemaciclib or placebo plus fulvestrant in hormone-receptor positive (HR+), real human epidermal development element receptor 2-negative (HER2-) advanced level breast disease that progressed on endocrine therapy. ...
In a recent paper, Alvarez and co-workers demon- strated a high [18F]FDG uptake, by glucose specific transporter 1 (GLUT1), in aggressive Her2-positive mammary tumors8. Moreover, in this high grade cancer, it has been demonstrated that the aerobic glycolytic metabolism correlates with tumor...
Ano1 was significantly more associated with breast cancer with the lower clinical stage (stage I or II), or triple-negative status. Mostly importantly, Ano1 overexpression was associated with good prognosis in patients with the PR-positive or HER2-negative status, and in patients following ...
Both white and black mustard seeds are excellent sources of melatonin. Melatonin protects against ER+ breast cancer by reducingaromatase activitywithin the breast, thereby decreasing estrogen production. Melatonin has also been found to reduce triple negative (ER-/PR-/HER2-) breast cancer growth, pro...
Anthocyanins have been shown to inhibit breast cancerproliferation,inflammationandangiogenesis(the formation of new blood vessels). Cyandin-3-glucoside in particular has been shown to reduceHER2+cell proliferation and interfere with the viability and metastatic potential of triple negative (ER-/PR-/HER2...