Wassall, Cholesterol is found to reside in the center of a polyunsaturated lipid membrane, Biochemistry 47 (2008) 7090-7096.Harroun, T. A.; Katsaras, J.; Wassall, S. R. Cholesterol is found to reside in the center of a polyunsaturated lipid membrane. Biochemistry 2008, 47 (27), 7090-...
The membrane insertion ability of Aβ is critically controlled by the ratio of cholesterol to phospholipids. In a low concentration of cholesterol Aβ prefers to stay in membrane surface region mainly in a β-sheet structure. In contrast, as the ratio of cholesterol to phospholipids rises above ...
Among the different lipid classes, cholesterol possesses particular properties: It is an essential structural component of cell membranes and a precursor of steroid hormones and bile acids. Cells gain cholesterol either by uptake from extracellular acceptors, such as lipoproteins, or by endogenous de ...
Lowering Cholesterol Naturally Learn how to lower your bad LDL cholesterol and improve your heart health with these 12 diet and lifestyle tips. Elaine K. HowleyandGretel SchuellerNov. 21, 2024 Foods to Stock for the Holidays Keep visitors nourished with these healthy breakfast, lunch and snack ...
The LM-LLO used in this study is attenuated, that is, the coding region for the C-terminal part of the LLO (cytolytic domain that binds cholesterol in the membranes) protein has been deleted, and mutations have been introduced into the prfA gene (expressed by the pGG34 vector), which ...
7-Dehydrocholesterol dictates ferroptosis sensitivity. Nature, https://doi.org/10.1038/s41586-023-06983-9 (2024). Tzelepis, K. et al. A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia. Cell Rep. 17, 1193–1205 (2016). Article CAS Pub...
CD14+CD16+ monocytes were counted using a five-type automated hematology analyzer; mononuclear cells were assessed using fluorescence-activated cell sorting; and an automatic biochemical analyzer was used to measure the levels of triglyceride, cholesterol, high- and low-density lipoprotein cholesterols,...
Question: Fill in the blank: A cell membrane is ___ allowing materials to enter and exit. Plasma Membrane: The cell, or plasma, membrane encloses the entire cell cytoplasm. It is made from a phospholipid bilayer in which proteins and cholesterol are embedded. Answer and Exp...
et al. ER-lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signaling in Niemann-Pick type C. Nat. Cell Biol. 21, 1206–1218 (2019). CAS PubMed PubMed Central Google Scholar Rizzuto, R. et al. Close contacts with the endoplasmic reticulum as determinants of...
A. Esterified cholesterol is highly localized to Bruch’s membrane, as revealed by lipid histochemistry in wholemounts of human choroid. J. Histochem. Cytochem. 57, 731–739 (2009). Article CAS PubMed PubMed Central Google Scholar Chuang, J. Z., Hsu, Y. C. & Sung, C. H. ...