CFTR is a tumor suppressor gene in murine and human intestinal cancer. Oncogene. 2016; 35: 4179-87. doi: 10.1038/onc.2015.483.Than BL, Linnekamp JF, Starr TK, et al. CFTR is a tumor suppressor gene in murine and human intestinal cancer. Oncogene 2016; 35: 4179-4187....
(MPH) is the first-line medicine for the treatment of children with attention-deficit hyperactivity disorder (ADHD); nonetheless, specific curative outcomes of MPH differ. Many reports have demonstrated that synaptosomal-associated necessary protein 25 (SNAP-25) gene MnlI polymorphisms may be ...
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togethers.Parkinson’s illness (PD) is a neurodegenerative condition brought on by the lacking of dopaminergic neurons. Many studies have illustrated that rotenone is used to determine the experimental style of PD, which simulates PD-like signs. FBXO22 is a poorly grasped necessary protein that ...
protein, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 4 (PFKFB4) ended up being found to be a mediator in FGF16-driven glycolysis and subsequent intrusion. Moreover, PFKFB4 had been found to try out a critical part to promote lactate-induced cellular intrusion since silencing PFKFB4...
Very similar effects of EMC disruption were observed for the tail-anchored protein squalene synthase (Figure 1B), a protein whose insertion into the ER is established to be EMC-mediated (Guna et al., 2018). Reporter cassettes lacking an insert or containing the cell surface protein asialo...
Cystic fibrosis is caused by a gene called CFTR. A. 相关知识点: 试题来源: 解析 B [概括大意] 见第三段第一句,“Cystic fibrosis is caused by defects in a gene called CFTR.”囊性纤维变性是由一种叫做CFTR的基因的缺陷所造成的。反馈 收藏 ...
1. Describe a condition or disorder (other than cystic fibrosis) that has been linked to mutations in the CFTR gene. 2. What are the health implications? Is an effective treatment and/or cure available? 3. What is CFTR responsible for? Cystic fibrosis is a genetic disease th...
What is a Hypomorphic loss of function mutation? Hypomorphic describes amutation that causes a partial loss of gene function. A hypomorph is a reduction in gene function through reduced (protein, RNA) expression or reduced functional performance, but not a complete loss. ...
Translation is a process part of the Central Dogma in biology where the genetic information in the RNA molecule will be translated into a polypeptide or protein. The RNA molecule is grouped into 3 nucleotide sequence which is known as codons. Using the genetic code table, each codon wil...