What is the cause of the lung disease cystic fibrosis? A. Tuberculosis B. Pneumonia C. Degradation of an active protein by ER quality control D. High level of cholesterol E. None Asthma, heart disease, and diabetes are all examples of what type of diseases? What are the ...
In sickle cell anemia, there is a replacement in the amino acid sequence of hemoglobin of glutamic acid by valine. What is the difference between glutamic acid and valine? a. Valine does not form a correct peptide bond. b. The protein resulting ...
Sickle cell diseaseis a hereditary disease caused by mutations in one of the genes that encode the hemoglobin protein. Red blood cells with the abnormal hemoglobin protein take on a sickle shape. The disease leads to chronic anemia and significant damage to the heart, lungs and kidneys. What d...
Hypomorphic describesa mutation that causes a partial loss of gene function. A hypomorph is a reduction in gene function through reduced (protein, RNA) expression or reduced functional performance, but not a complete loss. The phenotype of a hypomorph is more severe in trans to a deletion alle...
Heavy EC smoking promotes inflammatory processes (activator of transcription and nuclear factor-κB signaling, Janus tyrosine kinase/signal transducer, and mitogen-activated protein kinase), in a similar way to tobacco smoke. Protracted exposure to some components of EC vapor results in respiratory ...
Reversing and/or mitigating neurological damage has much to gain from the vast amount of data made available through scientific evidence, including epidemiological and clinical aspects of the disease, as well as genomic sequencing, biochemical characterization, enzymology, and resolution of protein ...
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AcronymDefinition TP3 Transport Protocol Class 3 TP3 Transition Protein 3 Copyright 1988-2018 AcronymFinder.com, All rights reserved. Suggest new definition Want to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the webmaster's page for free fun cont...
a transporter in hormone transport without adequate biochemical analyses. In cases where a protein of interest functions as a modulator of other transporters, it is necessary to carefully interpret transport activities/mutant phenotypes to elucidate functions of the modulator itself. Furthermore, ...
Hyde SC, Southern KW, Gileadi U, et al. Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis.Gene Ther. 2000;7:1156–1165. PubMedCASGoogle Scholar Noone PG, Hohneker KW, Zhou Z, et al. Safety and biological efficacy of a lipid-CFTR complex for...