Is Arginine Charged in a Membrane ? Biophysical Journal - Is Arginine Charged in a Memb ...Online, ActivateIssue, CurrentAlerts, EmailSearch, AdvancedManuscript, SubmitLi L, Vorobyov I, Mackerell AD Jr & Allen TW (2007). Is arginine charged in a membrane? Biophys J 94, L11-3....
To support our concept that lysines are effective through their positive charge, we generated N1•PB2>R in which the three lysine residues in PB2 were mutated to positively charged arginines. Indeed, N1•PB2>R underwent LLPS similarly to N1 (Fig. S4A). In contrast, mutation of the ...
To deliver useful biological payloads into the cytosolic space of cells, cell-penetrating peptides have to cross biological membranes. The molecular features that control or enhance this activity remain unclear. Herein, a dimeric template of the arginine
The three continuously conserved arginines (Arg68, Arg69, and Arg70) are located together in the α3 helix of LC3B, which may form a local positively charged area and serve as a potential protein-protein interaction sites. As mentioned above, only Arg68 can affect the cleavage of human Atg...
Presumably, the methylation at multiple charged sites dramatically altered the conformation of CFL1, hampering its function. Nevertheless, the lack of effect of in vitro SUMOylation on MeM1+25K-CFL1 induced F-actin disassembly (Fig. 4e, blue solid circles) validated that the enhancing effect ...
1B) with nearly full-length U2AF65 that lacks an aggregation prone arginine-serine repeat region (ΔRS), each N-terminally tagged with GST. To avoid overlapping molecular weights, we conversely compared GST–Tat-SF1 retention of SF3b1ULM with SF1. The SF1 protein was phosphorylated (P) ...
摘要: The 5′-terminal sequence m7G5′ ppp5′ GmpCp was isolated from Moloney murine leukemia virus 35S RNA after digestion of 32P-labeled RNA with RNases T1, T2, and A followed by pH 3.5 ionophoresis on DEAE paper.年份: 1976 收藏 引用 批量引用 报错 分享 全部来源 求助...
NADPH oxidase homologues were reported in a range of cells suggesting a role in cell signaling reviewed in [7]. Superoxide anions were to an extent ruled out as they were charged and deemed not able to pass through membranes, although once protonated this is not the case. Focus fell on ...
Phase separation of IDPs is driven by transient attractive interactions between specific amino acids, such as arginine and tyrosine, and non-specific electrostatic and hydrophobic interactions between residues [63]. It is assisted by the relatively small entropic cost when proteins move from a dilute...
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