Immunochemical difference between iron saturated and unsaturated human transferrin. Nature - FM, Burtin - 1968Kourilsky FM, Burtin P. Immunochemical difference between iron-saturated and unsaturated human transferrin. Nature 1968; 218: 375-377.
bLf restore the physiological internalization of Transferrin (Tf) Receptor 1, the molecular gate for Tf-bound iron uptake. The involvement of astrocytic antioxidant response in Tat-mediated neurotoxicity was evaluated in co-cultures of U373-Tat with human neuronal SH-SY5Y cells. The results show tha...
1. 常见形式: 每个转铁蛋白分子通过N端和C端结构域可结合两分子铁离子,一般以三种形态存在:脱铁转铁蛋白(apo-transferrin),饱和铁转铁蛋白(holo-transferrin),和部分饱和转铁蛋白(partially iron-saturatedtransferrin)。生理情况下,转铁蛋白分子仅有1/3被铁饱和。 2. 饱和铁(holo)到脱铁(apo)的转化机理 饱和...
This study evaluated the influence of apo‐ and ironsaturated lactoferrin (APOLF and FELF) and transferrin (APOTF and FETF), immunoglobulin G (IgG) and serum albumin (SA) at concentrations ranging from 0·02 to 2·5 mg ml‐1 on PBMC response to concanavalin A. PBMC were collected from ...
iron status in the brain, much like transferrin receptors sense systemic iron status in the gut through the amount of saturated transferrin. If this is the case, during brain iron sufficiency, holo-transferrin could be feeding back into the endothelial cell. The feedback system might result in ...
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英文名称: Transferrin, Human Plasma (SIDERO), Partially Iron Saturated, Tissue Culture Grade 总访问: 375 国产/进口: 进口 半年访问: 4 产地/品牌: Athens 产品类别: 分子生物学试剂 规格: 16-16-S32001-LEL 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
(2) A transferrin binding component which saturated at 0.5 μM diferric transferrin was detected. The number of specific, saturable diferric transferrin binding sites on mouse hepatocytes was 4.4·10 4±1.9·10 4 for cells in suspension and 6.6·10 4±2.3·10 4 for adherent cultured cells. ...
gingivalis in the acquisition of iron from human transferrin and its subsequent utilization in growth. Iron-saturated transferrin was found to support the long-term growth of P. gingivalis. Our results indicated that P. gingivalis does not produce siderophore and does not possess ferric reductase ...
As iron stored in the spleen is gradually released, plasma transferrin becomes saturated, leading to the presence of NTBI in the plasma. Transfusion-induced iron overload is characterized by elevated levels of NTBI, which has a strong affinity for parenchymal cells [29]. NTBI may serve as a ...