Bourel, Iron over- load of the liver in the baboon. An ultrastructural study, J. Hepatol. 1 (1985) 261-275.Iancu, T. C, Rabinowitz, H., Brissot, P., Guillouzo, A., Deugnier, Y., and Bourel, M., 1985, Iron overload of the liver in the baboon: an ultrastructural study, J....
iron overload have abnormalliver function teststhat are not obviously related to any other complication of HCT,1312,1317and in some cases these can clinically mimic other conditions (e.g. GVHD).1311,1318Liver biopsyis helpful in these patients, both to confirm the severity of iron overload ...
Experimental hepatic iron overload in the baboon: Results of a two-year study The mechanisms by which excess alcohol directly damages the liver cells have been elucidated by studies in the baboon, which have shown that inability of the liver''s enzyme systems to cope with hydrogen and fat ove...
systemic iron-loading conditions (hereditary hemochromatosis), conditions associated with systemic macrophage iron accumulation (transfusions, hemolytic conditions, anemia of chronic disease, etc), in some hepatitidies (hepatitis C, alcoholic liver disease, porphyria cutanea tarda), and liver-specific iron...
The pathogenesis of liver fibrosis in genetic haemochromatosis and other iron overload states remains enigmatic. Recent advances in the cellular and molecular pathogenesis of liver fibrosis have determined a central role for hepatic stellate cells. These become activated to a myofibroblastic phenotype fol...
Magnetic resonance imaging (MRI) has become the clinical standard to estimate liver iron overload. The most commonly used method is to measure the transversal relaxation time, T2*, from a multi gradient recalled echo sequence (MGRE). While this technique is reliable in low to moderate liver ir...
Iron overload: accuracy of in-phase and out-of-phase MRI as a quick method to evaluate liver iron load in haematological malignancies and chronic liver dis... Objectives: The purpose of this prospective study was to evaluate the accuracy of inphase and out-of-phase imaging to assess hepatic...
As the main organ of storing excess iron,liver is the first target organ damage when iron overload.However,the relation between nonalcoholic fatty liver di... T Peng - 《Chinese Journal of Gastroenterology & Hepatology》 被引量: 17发表: 2009年 Relationship between iron overload and nonalcoholi...
To evaluate the quantification of liver iron concentration using 1-Tesla magnetic resonance imaging (MRI) and its ability to diagnose or rule out hemochrom... JMA Echeverría,AC Eguzkiza,EZ Morcillo,... - 《Radiología》 被引量: 3发表: 2008年 Impact of Hepatic Iron Overload in the Evaluatio...
To understand if iron accumulation alters the pathogenesis of diabetic retinopathy, we induced diabetes in HFE KO mice, a genetic model of iron overload, using STZ. We reported previously that HFE KO mice have increased retinal iron accumulation with age-dependent retinal degeneration36,37. In the...