Iron deposition in liver in zidovudine-related transfusion-dependent anaemia. Lancet 1989; ii; 681.Lindley, R, Parkin, J, Dourakis, S, Goldin, R. (1989) Iron deposition in liver in zidovudine-related transfusion-dependent anaemia. Lancet 11: pp. 681...
Iron deposition in the liver and guts of giant South American freshwater turtle Podocnemis expansa (Schweigger 1812) from a commercial breeding farm in Acr... A Conrado,AD Oliveira,L Medeiros,... - 《Multidisciplinary Science Journal》 被引量: 0发表: 2022年 Avaliação da cavidade oro...
(a) Hepatic iron concentrations and (b) Perls' staining for iron deposition in liver sections ( Â 200 magnification). #Po0.05 compared with WT mice on chow only. *Po0.05 compared with nonethanol-treated animals within the same genotype and dietary group. factor-b1 (Tgf-b1) revealed the...
Two NBIA genes are directly involved in iron metabolism, but whether other NBIA-related genes also regulate iron homeostasis in the human brain, and whether aberrant iron deposition contributes to neurodegenerative processes remains largely unknown. This study aims to expand our understanding of these ...
Full-blown hemochromatosis is characterized by cirrhosis of the liver, darkening of the skin, diabetes, cardiomyopathies, and possibly by arthropathies. Iron deposition is primarily in hepatocytes, with macrophages and intestinal mucosal cells being relatively iron poor. The most common causes of ...
Imaging studies can also reveal findingssuggestive of iron overload. Magnetic resonance imaging (MRI) may be used to detect iron accumulation in the liver and the heart.1However, iron deposition is not reliably predicted by MRI in some instances, such as when iron deposition occurs in the pancr...
Although iron deficiency occurred commonly in the elderly, accumulation of iron in certain organs and tissues was observed, including brain, liver, spleen, kidney, and skeletal muscles, indicating malfunction of iron homeostasis [5, 22]. Iron deposition in senescent cells was observed, which was ...
in specific brain areas, but the reason why this increase is limited to some brain regions is still unclear. This physiological iron deposition during aging possibly contributes to senescence [9], while even higher iron accumulation occurs in the substantia nigra in Parkinson’s disease (PD) [10...
Alcohol-induced increase in hepatic transferrin receptor-1 expression and up-regulation of high iron protein in Kupffer cells (proposed) facilitate iron deposition and retention in the liver. Iron is loaded in both parenchymal and nonparenchymal liver cells. Iron-loaded liver can promote ferroptosis ...
Excess iron deposition in different regions of the brain with suspected toxicity has been identified by MRI T2* and similar methods in many neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. Based on its role as the major biological catalyst of free radical reactions...