The intrinsic and extrinsic pathways of apoptosis are both naturally occurring processes by which a cell is directed to programmed cell death. Both pathways of apoptosis activate cell signaling cascades that are an indispensable part of the development...
Miroslaw LancutKamila BulakJoanna Leszcz-StankiewiczBarbara Jodlowska-Jedrych生物医学工程(英文)Chylińska-Wrzos P. et al.: The intrinsic or the extrinsic pathways of apoptosis in the epidermis after cladribine application? Journal of Biomedical Science and Engineering, 6/3, 265, 2013....
The intrinsic or the extrinsic pathways of apoptosis in the epidermis after cladribine application?CladribineApoptosisCaspase 8Caspase 9EpidermisPurpose: This study was aimed toassess the expression of caspase 8 and caspase 9 in the epidermis, duringapoptosis after cladribine administration. Materials and ...
Intrinsic & Extrinsic pathways of Apoptosis 来自 ResearchGate 喜欢 0 阅读量: 11 作者: NS Al-Ammar 摘要: Is a pathway of cell death in which cells activate enzymes that degrade the cells' own nuclear & cytoplasmic proteins. DOI: 10.13140/RG.2.2.34144.69122 年份: 2016 ...
//journals.tubitak.gov.tr/medical Part of the Medical Sciences Commons Recommended Citation BUYUK, BURCU PELİN; CANSARAN DUMAN, DEMET; and DUMAN, TURKER (2024) "BRAF inhibitor candidate molecule usnic acid might use both intrinsic and extrinsic pathways of apoptosis," Turkish Journal of Medical...
At the same time, expression of pro-apoptotic genes such as p53, Caspase-3, 8, 9, Bid and Bax were significantly up-regulated by the treatment with harmine, which indicated the involvement of harmine in both intrinsic and extrinsic pathways of apoptosis. Cell death mechanism induced by the...
aTwo principal pathways for apoptosis initiation exist. One pathway, which is also termed the ‘extrinsic’ pathway, is mediated by death receptors, a subgroup of the TNF receptor superfamily. The second pathway, which is also referred to as the‘intrinsic’pathway, is controlled by members of ...
We show that megakaryocytes possess a Fas ligand-inducible extrinsic apoptosis pathway. However, Fas activation does not stimulate platelet production, rather, it triggers Caspase-8-mediated killing. Combined loss of Caspase-8/BAK/BAX does not impair thrombopoiesis, but can protect megakaryocytes ...
Here, we discuss the growth, development, and function of NK cells in regard to intrinsic and extrinsic factors. Intrinsic factors are those that influence NK cells to promote cell maturation and exert their effector functions under the control of internal metabolism and self-related genes. ...
H1N1 and H3N2 prefer to initially enhance the intrinsic pathway, determined by higher caspase 9 activity in MDCK II cells compared to caspase 8 activity and vice versa in A549 cells at different MOIs, while INF B prefers extrinsic pathway in A549 cells according to significant low or ...