The expression of alpha 2 beta 1 integrin and alpha smooth muscle actin in fibroblasts grown on collagen [ J ]. Cell Biochem Funct, 1998,16 (2): 129 - 137.Ehrlich HP,Cremona O,Gabbiani G. The expression of alpha 2 beta 1 integrin and alpha smooth muscle actin in fibroblasts grown ...
Traumatic brain injury (TBI) is a serious public health issue that poses a significant threat to human health and well-being, and it is one of the leading causes of death and disability worldwide [1, 2]. TBI can be categorized into primary and secondary brain injuries. Within minutes of ...
The 2 integrin intercellular adhesionmolecule (ICAM) adhesion pathway is likely pivotal inthe immunopathogenesis of inflammatory bowel disease(IBD). We have undertaken a comprehensive study ofperipheral blood lymphocyte (PBL) expression of all2 integrins and ICAMs in patients with IBD usingflow cytometry...
Our results provide a new perspective on the role of PIP2 in integrin activation and indicate that the charged PIP2 lipid headgroup can perturb a clasp at the cytoplasmic face of the integrin heterodimer. 展开 DOI: 10.1021/acs.jpcb.5b06457 被引量: 12 ...
Table 1 Changes in mRNA expression from culturing monocytes on soft, anti-fibrotic (1 kPa) and stiff, pro-fibrotic (12 kPa) surfaces, assessed by RNAseq. Full size table Table 2 Changes in mRNA expression from culturing monocytes on soft, anti-fibrotic (1 kPa) and stiff, pro-fibrotic (...
ChemicalBook 致力于为化学行业用户提供Integrin β2 (E9O7W) Rabbit mAb (BSA and Azide Free)的性质、化学式、分子式、比重、密度,同时也包括Integrin β2 (E9O7W) Rabbit mAb (BSA and Azide Free)的沸点、熔点、MSDS、用途、作用、毒性、价格、生产厂家、用途、上游原料
Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system Razan Wafai, Elizabeth D. Williams, Emma de Souza...
Recombinant α2 I-domain protein bound HRG and to a higher extent when in active conformation. However, the α2 I-domain bound weakly to HRG compared with COL I and the purified α2β1 ectodomain complex failed to retain HRG. We conclude that HRG binds to α2 integrin through low-...
Conclusions: Up-regulation of TGF-β2 and TN suggested that an increased amount of mechanical stress existed in the conjunctivae of the SLK patients. In addition, deposition of TN and suprabasal expression of integrin β1 suggested that chronic minor injury contributed to the pathogenesis of SLK...
Fab to the β2 I-like domain converts firm adhesion to rolling adhesion, but does not enhance adhesion. Residue αL-Glu-310 in the linker following the I domain is critical for communication to the β2 I-like domain, rolling, integrin extension, and activation by Mn2+ of firm adhesion....