consisting of integrin尾2 and尾3,were identified and used to understand the development of plasmatocytes.Plasmatocytes are widely distributed in the hematopoietic system,including circulating hemolymph and hematopoietic organs(HPOs).HPOs constantly release plasmatocytes with high proliferative activity in...
These receptors appear to be the key receptors utilized by cancer cells for the initial attachment to cortical bone, and this could facilitate the localization of α2 1and α3 1expressing cancer cells to the skeleton. 展开 关键词: breast cancer attachment bone collagen integr ...
EGFRvIII/integrin β3 interaction in hypoxic and vitronectinenriching microenvironment promote GBM progression and metastasis 来自 NCBI 喜欢 0 阅读量: 119 作者:Z Liu,L Han,Y Dong,Y Tan,H Ren 摘要: Glioblastoma (GBM) is one of the most lethal brain tumors with a short survival time. ...
BackgroundStem cells are precursors for all mammary epithelia, including ductal and alveolar epithelia, and myoepithelial cells. In vivo mammary epithelia reside in a tissue context and interact with their milieu via receptors such as integrins. Extracellular matrix receptors coordinate important cellular...
Fig. 2: Expression of the integrin α3 subunit is elevated in TECs from human glioblastoma compared to NECs. a, b Total RNA was extracted from 3 NECs (376, 422, and 623) and 3 TECs (isolates cw880, ccf2352, and ccf2390) when similar densities of tubes had formed on Matrigel, and...
Myofibroblasts are key to the progression and maintenance of fibrosis. We investigated features of cell adhesion necessary for monocytes to differentiate into myofibroblasts, seeking to identify pathways key to myofibroblast differentiation. Blocking antibodies against integrins α3, αM, and αMβ2 de-...
Therefore, the aim of this study was to determine the porcine zona pellucida glycoprotein 3 (pZP3) and integrin β2 (ITGB2) transcript and protein levels after single and double exposure to BCB. Section snippets Animals A total of 39 pubertal crossbred Landrace gilts with median age of 170 ...
A competition experiment was performed by the co-injection of a saturating dose of bicyclic RGD peptide H-Glu[cyclo(Arg-Gly-Asp-D-Tyr-Lys)]2 (n = 3). Following image acquisition and sacrifice at 24 hours after injection, carotid arteries were harvested for histological analyses. Neointima ...
as well as the mechanisms by which these adaptors and co-receptors function, are still being discovered.Using shRNA, blocking antibodies, and fluorescent microscopy, we show that U937 macrophage responses to the TLR2/1 ligand, Pam(3)CSK(4), are dependent upon an integrin, α(3)β(1). Th...
Fig. 2 Examples of selective integrin ligands [15,30,31,32,33,34] whose radiolabeled derivatives were developed and/or evaluated in the framework of CRC 824. Note that all addressed integrins (αvβ3, αvβ6, αvβ8, α5β1) belong to the class of RGD receptors (seeFig.1), but ...