Intact Mass Analysis Charge Variant Analysis Protein Aggregate Analysis 滴度(亲和)分析 天然完整蛋白质量分析 Subunit Mass Analysis Deliver unequivocal intact mass assignments Among the analytical tools used for the characterization of proteins, high-resolution accurate-m...
Intact protein mass spectrometry workflow Featured chromatography solutions for intact mass analysis Intact protein chromatography built for biopharma Thermo Scientific Vanquish Flex UHPLCdelivers confidence, with a fully bio-compatible flow path and proven compliance. A...
Intactmassanalysisofmonoclonalantibodiesbycapillary electrophoresis—Massspectrometry MeiHan ∗ ,BrookeM.Rock,JoshT.Pearson,DanA.Rock PharmacokineticsandDrugMetabolism,AmgenInc.,1120VeteransBoulevard,SouthSanFrancisco,CA,USA articleinfo Articlehistory:
Native MS and other charge reduction strategies yield increased spectral separation to allow the accurate intact mass analysis of such highly complex spectra. We present a semi-automated workflow for analyzing high mass PEG-protein conjugates utilizing native ion exchange coupled directly to an ultra-...
Intact Mass Analysis of Monoclonal Antibody (MAb) Charge Variants Separated Using Linear pH Gradient 来自 掌桥科研 喜欢 0 阅读量: 4 作者:S Lin,Z Hao,W Decrop,J Baek,U Aich,P Bennett,S Rao,Y Agroskin,C Pohl,D Milton 摘要: A linear pH gradient from pH 5.6 to pH 10.2 was generated ...
Intact Mass 1.3 原因 首次导入数据时,modifiedDate 列中没有日期,时区偏移将其设置为比缺省最小值早一小时。这是一个已知问题,将在未来的版本中修复。 解决方法 在Explorer 中创建一个新的 Temporary Import 文件夹。 将数据导入 Explorer 的 Temporary Import 文件夹。
Functions such as discovery screening, process development, and formulations/stability can generate a large number of samples, and analytical solutions that can achieve high-throughput intact mass analysis and impurity profiling are adva...
Functions such as discovery screening, process development, and formulations/stability can generate a large number of samples, and analytical solutions that can achieve high-throughput intact mass analysis and impurity profiling are adva...
Intact mass analysis of monoclonal antibodies by capillary electrophoresis-Mass spectrometry. Characterization of monoclonal antibody (mAb) therapeutics by intact mass analysis provides important information on sequence integrity and post-translatio... H Mei,BM Rock,JT Pearson,... - 《J Chromatogr B ...
Henry Shion, Principal Scientist at Waters, discusses implications from his tech brief, which illustrates how high-quality, consistent intact mass analysis is possible over an extended period of time on not just one, but multiple Bioaccord systems. ...