Insulin resistance in humans is not always accompanied by obesity, since severe insulin resistance also characterizes patients lacking subcutaneous fat such as those with HAART- (highly-active antiretroviral therapy)-associated lipodystrophy. Both obese and lipodystrophic patients, however, have an increase...
et al. Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans. Diabetes Care 29, 853–857 (2006). Article CAS PubMed Google Scholar Auberger, P. et al. Characterization of a natural inhibitor of the insulin receptor ...
Insulin Resistance: Insulin Action and Its Disturbances in Disease. Chichester: John Wiley & Sons Ltd.; 2005:207-35. :Philip G Mc Ternan, Aresh Anwar and Sudesh Kumar, `Relationship between fat distribution and insulin resistance ; Insulin Resistance (Text Book); p 207-225, 2005....
insulin resistance syndrome caused by mutations in the insulin receptor gene can often show severe insulin resistance and hyperinsulinemia,but often without obvious fat accumulation.These studies suggest that type 2 diabetes with fat accumulation may not only be driven by insulin resistance,but also ...
Insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin, a hormone made by your pancreas that helps manage your blood glucose (blood sugar). Sometimes, insulin resistance is a short-term condition. But if left untreated for a long time, it could tu...
If there is a good deal of belly fat and/or a low level of daily physical activity, the risk is higher. What can be done about this? Is it a one-way road to disease?No it is not! Increasing physical activity and weight loss will reduce the insulin resistance and reduce your risk ...
et al.α2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans. Diabetes Care 29, 853–857 (2006). This paper described the discovery of fetuin A as a liver-secreted protein that is increased with steatosis and diabetes mellitu...
Lewis GF, Carpentier A, Adeli K, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocrine Reviews 2002;23:201–229. ArticlePubMedCASGoogle Scholar Farese RV, Jr., Yost TJ, Eckel RH. Tissue-specific regulation of lipoprotein lipa...
This process is closely associated with endoplasmic reticulum stress, insulin resistance (IR) as well as hepatocyte growth and proliferation (Geng et al., 2015; Geng et al., 2016b; Wei et al., 2022b). A recent study suggests that the large amount of fat stored in goose liver results ...
It should be pointed out that insulin levels in our blood often spike, which can also have serious consequences. If the insulin level in our blood constantly rises, it will gradually make the body's cells less sensitive to insulin, c...