Insulin resistance and the pathogenesis of nonalcoholic fatty liver disease. Clin Liver Dis. 2004; 8 :575–594. doi: 10.1016/j.cld.2004.04.006. [ Cross Ref ]Choudhury J, Sanyal AJ (2004) Insulin resistance and
Hepatic steatosis is a strong predictor of the development of insulin resistance and often precedes the onset of other known mediators of insulin resistance. This sequence of events suggests that hepatic steatosis has a causal role in the development of insulin resistance in other tissues, such as ...
Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without DiabetesThe accumulation of excess fat in the liver (hepatic steatosis) in the absence of heavy alcohol consumption causes nonalcoholic fatty liver disease (NAFLD), which has become a global ...
Insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin, a hormone made by your pancreas that helps manage your blood glucose (blood sugar). Sometimes, insulin resistance is a short-term condition. But if left untreated for a long time, it could tu...
It is known that endoplasmic reticulum stress (ERS) contributes to insulin resistance (IR) and non-alcoholic fatty liver disease (NAFLD) in mammals. However, we recently demonstrated that overfeeding with a traditional diet (mainly consisting of cooked maize) does not induce ERS in goose. As ce...
Insulin resistance in humans is not always accompanied by obesity, since severe insulin resistance also characterizes patients lacking subcutaneous fat such as those with HAART- (highly-active antiretroviral therapy)-associated lipodystrophy. Both obese and lipodystrophic patients, however, have an increase...
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the developed world, with a global prevalence of around 25%. NAFLD is considered to be the hepatic manifestation of metabolic syndrome and is strongly associated with obesity, insulin resistance and dysli...
NAFLD encompasses a broad spectrum of fatty liver disease, ranging from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH), and is strongly associated with obesity, insulin resistance, and dyslipidemia. First-line therapy for NAFLD includes weight loss achieved through diet...
Fatty Liver Disease In non-alcoholicfatty liver disease(NAFLD), too much fat builds up in your liver and damages this organ. Insulin resistance is one factor that drives this fat accumulation, according to a review inDiabetes Spectrum. People with NAFLD are twice as likely to develop type 2 ...
Check out thisreport by Yaleon the latest research linking insulin resistance to fatty liver disease. Learn more about metformin in thisreview published by the Mayo Clinic. Bibliography American Diabetes Association.Understanding insulin resistance.https://www.diabetes.org/healthy-living/medication-treatmen...