Testosterone activated the incorporation of labeled precursors into RNA and protein and the formation of 14CO... RS Santti,R Johansson - 《Experimental Cell Research》 被引量: 74发表: 1973年 Tetracycline and Incorporation of Amino Acids into Proteins Of Rat Tissues E. (1966) Tetracycline and ...
number of tissues accumulate small amounts of insulin, the liver and kidney are the principal sites of hormone uptake and degradation. Insulin metabolism is accomplished both through the actions of an insulinspecific protease found in the cytosol of many tissues and by the reductive cleavage of ...
Biology of ReproductionZhang X,Armstrong D T.Presence of amino acids and insulin in a chemically defined medium improves development of 8-cell rat embryo in vitro and subsequent implantation in vivo[J].Biol Reprod,1990,42:662-668.Zhang X, Armstrong DT (1990):Presence of amino acids and ...
INSULIN, with the chemical formula C254H377N65O75S6 and CAS registry number 11070-73-8, is a peptide hormone produced by the pancreas. It plays a crucial role in regulating blood sugar levels by facilitating the uptake and storage of glucose in cells. Insulin is essential for the metabolism...
Scientific Reports volume 5, Article number: 11603 (2015) Cite this article 3306 Accesses 4 Citations 2 Altmetric Metrics details Abstract Insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF1R) signalling is required for normal embryonic growth and development. Previous reports ...
Insulin receptor (IR) controls growth and metabolism. Insulin-like growth factor 2 (IGF2) has different binding properties on two IR isoforms, mimicking insulin’s function. However, the molecular mechanism underlying IGF2-induced IR activation remains u
A hormone consisting of two polypeptide chains, rHu Insulin′s A-chain (21 amino acids) and B-chain (30 amino acids) are covalently linked by disulfide bonds between cysteine residues. This genetically engineered human insulin is a full sequence molecule producted by recombinant DNA technology in...
Fatty acids can modify proteins as substrates to alter cell signaling19. Amino acids are newly identified modifiers of proteins. Aminoacyl tRNA synthetases (ARSs) are aminoacyl transferases that catalyze the lysine aminoacylation of its cognate amino acid to proteins to regulate a number of physiolog...
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and ...
(Supplementary Fig.5e). In addition, sub-diffraction co-occurrence analysis of STED images indicated a marked decrease in the number of protein clusters (Fig.4k), and PLA analysis using insulin receptor and β-dystroglycan antibodies showed a decrease in insulin receptor-β-dystroglycan association ...