Innate lymphoid cells (ILCs) are white blood cells derived from a common progenitor in the bone marrow. They respond rapidly to a limited array of antigens at the site of infection to provide immediate protection. The first identified ILCs were natural killer cells. However, several non-...
Innate lymphoid cells (ILCs) are a group of innate effectors with transcriptional, functional, and phenotypic similarities to various T helper (Th) subsets. Like Th subsets, ILCs are found atmucosal surfacesand play important roles in...
Innate lymphoid cells (ILC) are instrumental to immediate, local response to pathogens. Here the authors use parabiosis and multiplex 3D imaging to identify a mouse type 3 ILC population that resides in the intravascular space of lung, produces CCL4 for neutrophil recruitment, and protects from Pse...
固有淋巴样细胞(innate lymphoid cells,ILCs)——来源于骨髓共同淋巴样前体,由转录因子ID2+固有淋巴样前体发育分化而成。包括ILC1/2/3三个亚群, 以及NK细胞。不表达特异性/泛特异性抗原受体,故其活化不依赖于对抗原的识别。此类淋巴细胞表达一系列与其活化或抑制相关的受体,可被感染部位组织细胞产生的某些细胞因子或...
先天性淋巴细胞（Innate Lymphoid Cells）先天免疫系统由⼀系列进化上古⽼的造⾎细胞组成，包括树突状细胞、单核细胞、巨噬细胞和粒细胞。这些细胞群相互协作，与适应性免疫系统和⾮造⾎细胞，以促进免疫，炎症和组织修复。先天性淋巴细胞是最近发现的先天性免疫系统的组成部分，在过去五年中⼀直是研究的热点。
Innate lymphoid cells (ILCs) are newly identified members of the lymphoid lineage with emerging roles in mediating immune responses and in regulating tissue homeostasis and inflammation. The existence of different ILC populations that can rapidly secrete immunoregulatory cytokines suggests that these cells ...
既往研究确定了2型固有淋巴细胞(innate lymphoid cells, ILCs)在小鼠肝纤维化发展中的作用,但ILCs在人类肝细胞癌(HCC)中的生物学功能仍不清楚。关于肝癌肿瘤微环境中调控ILCs的细胞因子的动态变化知之甚少。本项研究发现调控ILCs的细胞因子在非肿瘤和肿瘤组织中差异表达,并与TCGA-HCC队列中的预后相关。ILCs的轨迹分析...
Among these newly identified innate lymphoid cells is a subset sharing phenotypic characteristics of natural killer cells and lymphoid tissue inducer cells. These cells co-express the transcription factor RORγt and activating NK cell receptors (NKR), but their lineage and functional qualities remain ...
Blog Tag: Innate Lymphoid Cells Immunology News: Researchers Report the Identification of a New Regulatory Innate Lymphoid Cell Subset that Suppresses Innate Intestinal Inflammation Regulatory ILCs Suppress ILC1- and ILC3-Induced Innate Intestinal Inflammation...
Innate Lymphoid Cells (ILC) are tissue-resident effector lymphocytes that differ from the B and T lymphocytes subsets since they lack specific antigen receptors derived from gene rearrangements. They can be divided into two groups, cytotoxic ILC (NK cells) which are dependent on the transcription ...