In free-living organisms, including Escherichia coli , DNA replication starts at replication origins. E. coli contains a single replication origin ( oriC ), which serves as the site for assembly of the replisome, a multi-protein molecular machine that duplicates the circular duplex genome. ...
网络复制启动 网络释义 1. 复制启动 DNA复制启动(DNA replication initiation) 19: cdc34 cdc45l cdc7 mcm2 mcm3 mcm4 mcm5 mcm6 mcm7mcm8 mcmdc1 myt2 … www.uscnk.cn|基于 1 个网页
During the initiation of DNA replication, oligonucleotide primers are synthesized de novo by primases and are subsequently extended by replicative polymerases to complete genome duplication. The primase-polymerase (Prim-Pol) superfamily is a diverse grouping of primases, which includes replicative primas...
Integrative suppression of temperature-sensitive mutants iwth a lesion in the initiation of DNA replication. Replication of autonomous plasmids in the supp... A number of F-like transmissible plasmids (R1 drd16, F'lac and Hly-PM152), but bot the non-transmissible plasmids ColE1 and ColE2, ca...
The key genetic process of DNA replication is initiated at specific sites referred to as replication origins. In eukaryotes, origins of DNA replication are not specified by a defined nucleotide sequence. Recent studies have shown that the structural context and topology of DNA sequence, chromatin fea...
DNA replication. 1. Introduction Bacteriophage T7 has evolved an efficient and rapid mechanism for the replication of its DNA. Within 15 minutes of infection of an Escherichia coli cell, the 39,936 base-pair DNA molecule (Dunn & Studier, 1983) is duplicated more than 100 times. (iene...
DNA replication, the key determinant of cell proliferation, is a highly regulated process whose objective is to ensure that the genetic information encoded in the chromosomes is faithfully transmitted from parental to progeny cells. Failure in this regulation could lead to abnormal proliferation and gen...
The process of DNA replication must be very carefully controlled so that each daughter cell ends up with the same DNA content as its parent cell. In eukaryotic cells with multiple chromosomes, failure in this careful control can result in missing chromosomes or extra copies of chromosomes, a ...
专业医学词典 DNA复制起始 与"DNA replication initiation"相近的词条 ...
One of the mechanisms controlling the initiation of DNA replication is the dynamic interaction between Cdt1, which promotes assembly of the pre-replication license complex, and Geminin, which inhibits it. Specifically, Cdt1 cooperates with the cell cycle protein Cdc6 to promote loading of the minic...