DNA replication can be separated into three distinct steps: initiation at an origin of replication, elongation, and termination. The vast majority of studies of DNA replication in prokaryotic and eukaryotic systems have been dedicated to understanding the nature and regulation of the events occurring ...
Prokaryotic Replication Origins: Structure and Function in the Initiation of DNA ReplicationDnaAinitiator proteininitiation of replicationoriCreplication origindoi:10.1038/npg.els.0003900MesserWalter
DNA replication can be separated into three distinct steps: initiation at an origin of replication, elongation, and termination. The vast majority of studies of DNA replication in prokaryotic and eukaryotic systems have been dedicated to understanding the nature and regulation of the events occurring ...
The replicon model, proposed by Jacob and Brenner (1963) to explain the regulation of prokaryotic DNA replication, has proved remarkably robust. Despite the manyvariations in initiation mechanism discovered since 1963, the replicon model may be applicabl
Describe the replication of DNA only in the lagging strand. Describe the various steps involved in the initiation of replication in eukaryotes. What proteins are involved in each of the steps, and when in the cell cycle does each of them occur? How does their temporal segregation contribute to...
Small circular DNAs of 1.8 and 2.4?kb were initially discovered in highly infectious Creutzfeldt‐Jakob Disease (CJD) and scrapie particles from mammalian brain and cultured cells. Surprisingly, these protected cytoplasmic "SPHINX" DNAs contained replication (REP) initiation sequences resembling those ...
The sequence-specific endoribonuclease activity, rather than direct inhibition of DNA replication initiation, is responsible for plasmid maintenance [43,44]. There is a discrepancy in the proposed consensus sequence [43,44]. The earlier study of in vitro digestion of Toxins 2017, 9, 140 8 of ...
DNA synthesis in bacteria starts with the initiation of replication at a specific nucleotide sequence. Then, elongation occurs to add new nucleotides. Next, termination happens after the new chromosome forms. Gene Expression in Prokaryotes In prokaryotes, gene expression happens in a different way. Bo...
Dynamic Control of the DNA Replication Initiation Protein DnaA by Soj/ParA genes parA, parB, and parS are present in bacterial genomes throughout the prokaryotic evolutionary tree and are required for accurate chromosome segregation... H Murray,J Errington - 《Cell》 被引量: 258发表: 2008年 ...
Single-stranded (ss) DNA viruses are a major component of the earth virome. In particular, the circular, Rep-encoding ssDNA (CRESS-DNA) viruses show high diversity and abundance in various habitats. By combining sequence similarity network and phylogenetic analyses of the replication proteins (Rep...