Pyogranulomatous inflammation of the spleen.Mohamed E. MoustafaBradley A. CarlsonMiriam R. AnverGerd BobeNianxin ZhongJerrold M. WardChristine M. PerellaVictoria J. HoffmannKeith RogersGerald F. Combs Jr
Cells from the spleen and lymph nodes of ActbECFP reporter or Ccr9−/− mice were isolated by being passed through a steel wire mesh, filtered on a 40-μm cell strainer and after red blood cells lysis using ACK buffer. To enrich for T cells, single-cell suspensions were first incuba...
response to cellular injury [7]. This process correlates with the inflammasome activation, a molecular platform that results in the release of cleaved-caspase-1 and the production of interleukin (IL)-1β/18 in response to intracellular and extracellular stimuli [8]. The gasdermins (GSDMs) also...
weight and size of the enlarged spleen due to improvement in the edema, skin lesion recovery, and inflammation response in a lupus-related disease model ... EJ Kim,JH Choi,JA Kim,... 被引量: 0发表: 2022年 Or prevention of inflammatory diseases and pharmaceutical compositions method of treat...
Using this model we found that γδ T cells were still plentiful among the infiltrating T lymphocytes, being 9- to 10-fold more prevalent than in spleen, and that Vγ6/Vδ1+ cells again represented the predominant γδ T cell type. This finding shows that the response of the Vγ6/V...
A 7-week swimming program (1 or 1.5 hours per day, 5 days per week) ameliorated DSS-caused colon shortening, colon barrier disruption, spleen enlargement, serum LDH release, and reduction of body weight gain. Swimming for 1.5 hours per day afforded greater protection than 1 hour per day. ...
The cholinergic antiinflammatory pathway (CAP), which terminates in the spleen, attenuates postoperative cognitive decline (PCD) in rodents. Surgical patients with metabolic syndrome exhibit exaggerated and persistent PCD that is reproduced in postoperative rats selectively bred for easy fatigability and th...
Furthermore, the allo-transplantation–induced immunophenotype disorders of the spleen, including regulatory T (Treg), T helper (Th)1, Th2 and Th17, were attenuated in both cell-treated groups. MSCs-HGF treatment reduced expression and secretion of inflammation cytokines interferon-gamma (IFN-γ),...
Given the vital roles of ADSC-EVs in controlling inflammation across various diseases, a number of studies now have focused on their clinical application. However, systemic administration often leads to extensive accumulation of these vesicles in the liver and spleen, with rapid clearance that results...
Genetic deletion or inhibition of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin Arupture of the spleen... KS Kirkwood,I Castagliuolo,J Maa,... - 《Gastroenterology》 被引量: 3发表: 2000年 AMPKα2 deletion exacerbates neointima formation by upregulatin...