DepressionLongitudinal designOlanzapineSchizophreniaDepressive symptoms are frequent clinical manifestations in patients with schizophrenia. Decreased brain-derived neurotrophic factor (BDNF) has been shown to be involved in the development of depressive symptoms. However, the detailed molecular mechanism of BDNF...
treatment of MDD.10 IL-1β and TNF-α are generally thought to enhance sleep; however, extreme elevations in IL-1β and TNF-α can impair sleep.11,12 Sleep disturbances can present as either insomnia or hyper- somnia in MDD, with hypersomnia as a defining symptom of atypical depression....
Conclusions Xiaoyu granules could improve the depressive rats and the mechanism involving with increasing the expressions of NGF and BDNF in cortex and hippocampus. 展开 关键词: Xiaoyu granules Depression NGF BNDF 被引量: 1 年份: 2016 收藏 引用 批量引用 报错 分享 ...
With aging, the frequency of occurrence of depression is increasing in the women with low level of physical activity [22]. And, higher social activity is related to a lower risk of depression [22]. This means that lower physical activity induces lower physical function and ability of activity ...
Electroconvulsive therapy (ECT) is a long-standing treatment choice for disorders such as depression when pharmacological treatments have failed. However, a major drawback of ECT is its cognitive side effects. While numerous studies have investigated the therapeutic effects of ECT ...
No significant up-regulation of BDNF was observed in the ZnY group. We conclude that combined administration of zinc and folic acid can improve the symptoms of depression-model rats, and its mechanism is related to increased levels of 5-HT, DA and NE in the brain, and to the up-...
High baseline BDNF serum levels and early psychopathological improvement are predictive of treatment outcome in major depression. Psychopharmacology 231 (15), 2955-2965.Mikoteit T, Beck J, Eckert A, Hemmeter U, Brand S, Bischof R, Holsboer-Trachsler E, ini- Stula A (2014) High baseline ...
Results: From the results of the study it was found that the mean of Hamilton Depression Rating Scale (HDRS), the Indonesian version of the Montreal Cognitive Assessment (MoCA-Ina) and Brain-Derived Neurotrophic Factor (BDNF) serum levels in the samples given by both gro...
DepressionHypersomniaInsomniaRepetitive transcranial magnetic stimulation (rTMS)BDNF brain-derived neurotrophic factorCDRS-R Children's Depression Rating Scale, RevisedDSM-IV-TR Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision...
17尾- Estradiol replacement in young, adult and middle-aged female ovariectomized rats promotes improvement of spatial reference memory and an antidepressant effect and alters monoamines and BDNF levels in memory- and depression-related brain areas. Behav Brain Res 2012;227:100-8....