(ICD). A form of cell death that leads to the recognition of dead-cell antigens by T lymphocytes. Immunogenicity The capacity of an entity to induce an immune response based on the combination of antigenicity and adjuvanticity. Integrated stress response (ISR). A phylogenetically ancient stress...
Data are from the Multiple Cause of Death Files, 1999–2019, as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program.” Retrieved from http://wonder.cdc.gov/ucd-icd10.html Centers for Disease Control and Prevention (CDC) 2021a. ...
(PDF 72 kb) Abbreviations AGW: Anogenital wart; CI: Confidence interval; EMA: European Medicines Agency; GePaRD: German Pharmacoepidemiological Research Database; HPV: Human papillomavirus; ICD-10-GM: International Classification of Diseases, Version 10, German modification; IQR: Interquartile range; ...
The database contains demographic data, in- and outpatient diagnoses recorded according to the International Classification of Diseases (ICD-10-GM), in- and outpatient diagnostic and therapeutic procedures, and outpatient drug prescriptions. Outpatient diagnoses can only be allocated to a quarter of a...
[39]. Specifically, mouse-derived tumor cells are exposed to a potential ICD inducer ex vivo and then administered as a vaccine in the absence of any immunological adjuvant after the removal of exogenous chemical entities, such as the ICD inducer. After 7 to 10 days, mice are ...
Rosa's Model Qualification Method was used to document the design, testing criteria, uncertainties, and patient variability. Integration of existing data and knowledge into a mechanistic model facilitated new insights into the pathophysiology and SOC therapies of acne and identified knowledge gaps. The ...
(ICD). SP: signal peptide; TM: transmembrane domain.cSchematic diagram of phosphorylated sites, S279 and S283 in the ICD of PD-L1. Positions of phosphorylated sites were labeled in red. This image was created by the first author.dImmunoblots of PD-L1 (anti-Flag) in HEK293T cells ...
Subsequently, long-term antitumor immune response was examined by testing memory T cells (TEM) in spleen. FA-TSL/AuNCs/SV + laser group significantly increased TEM frequency in spleen, whereas FA-TSL/AuNCs/SV and FA-TSL/AuNCs + laser showed moderate efficacy to generate TEM (Supporting ...
ICD: Immunogenic cell death IFN: Interferon IL-24: Interleukin iRGD: Internalizing RGD ITR: Inverted terminal repeats L1-L5: Late genes LOAd: Lokon oncolytic adenovirus MAGE: Melanoma-associated cancer-testis antigen MSC: Mesenchymal stem cell MYXV: Myxoma virus NK: Natural killer ...
[39]. Specifically, mouse-derived tumor cells are exposed to a potential ICD inducer ex vivo and then administered as a vaccine in the absence of any immunological adjuvant after the removal of exogenous chemical entities, such as the ICD inducer. After 7 to 10 days, mice are ...