Macrophage-derived TNFB (LTA) andIL1Balso contribute to beta-cell death through the caspase cascade. LTA binds to its receptor, TNFRSF1A, and stimulates further signal transduction leading to CASP10 and CASP2 activation. IL1B stimulates the induction of NOS2, nitric oxide (NO) generated by ...
重组人MCSF蛋白 | Recombinant Colony Stimulating Factor 1, Macrophage (MCSF) 重组人MCTS1蛋白 | Recombinant human MCTS1 protein 重组人mdh蛋白 | Recombinant human mdh protein 重组人MDH1蛋白 | Recombinant human MDH1 protein 重组人MDP1蛋白 | Recombinant human MDP1 protein ...
Monocyte / MacrophageBedaquiline (BDQ) is one of the modern antibiotics for MDR-tuberculosis (TB) therapy. Its immunomodulatory properties have not yet been studied. The aim of our work was to reveal BDQ effects on the functional activity of pro-inflammatory (M1) human macrophages.BDQ effects (...
PLoS One Macrophage expression of E3 ubiquitin ligase Grail protects mice from lipopolysaccharide-induced hyperinflammation and organ injury Pubmed: 30571701 BBA- Molecular Basis of Disease Enhanced remedial effects for vitamin D3 and calcium co-supplementation against pre-existing lead nephrotoxicity in mic...
The main physiological source of IL-1 is activated macrophage (Figure 5-5), and it is created as a precursor called pro-IL-1. Its secretion can be triggered by varying proinflammatory stimuli, including cellinjury, products of thebacterial cell membranes,zymosan,leukotrienes, activatedcomplement co...
macrophageinterleukin-1High mobility group box 1 protein (HMGB1), originally described as a non-histone, DNA binding protein, was recently identified as a late mediator of inflammation via its extracellular release from activated macrophages/monocytes. In the present study, we report that intracellular...
Mucosal Immunology Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization Pubmed: 31086271 The role of amniotic fluid exosome, hypoxia inducible fator-1α, and inflammatory cytokine in cervical insufficiency pharmacological research Neuroprotection in non-...
macrophagePKMPKM2SQSTM1synovitisSynovitis is implicated in the pathology of osteoarthritis (OA) and significantly contributes to the development of OA. As a noninvasive physical therapy, low-intensity pulsed ultrasound (LIPUS) has been reported to possess anti-inflammatory effect in recent years. ...
macrophagePKMPKM2SQSTM1synovitisSynovitis is implicated in the pathology of osteoarthritis (OA) and significantly contributes to the development of OA. As a noninvasive physical therapy, low-intensity pulsed ultrasound (LIPUS) has been reported to possess anti-inflammatory effect in recent years. ...
High mobility group box chromosomal protein 1 (HMGB1) was recently identified as a late proinflammatory mediator of endotoxin lethality, which amplifies and sustains the inflammatory processes via macrophage/monocyte activation by extracellular release of HMGB1. However, it was originally described as a ...