Gene SummaryThis gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the...
Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the IL12A gene. Compositions and methods for haplotyping and/or genotyping the IL12A gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed ...
IL12A (Interleukin 12A, also known as P35; CLMF; NFSK; NKSF1; IL-12A), located on 3q25.33, is a Protein Coding gene. The gene produces a 24874 Da protein composed of 219 amino acids. IL12A is a subunit in 2 distinct heterodimeric cytokines: interleukin-12 (IL12) and IL35. IL12 is...
1. Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. ...
Target NameIL12A Alternative NamesP35; CLMF; NFSK; NKSF1; IL-12A Accession No.Swiss-Prot:P29459 Gene Accssion:NP_000873 UniprotP29459 Gene ID3592; Concentration1.2mg/ml FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
背景资料Interleukin-12 subunit alpha (IL-12 p35) is a protein that in humans is encoded by the IL12A gene.This gene encodes a subunit of a cytokine that acts on T and natural killer cells,and has a broad array of biological activities.The cytokine is a disulfide-linked heterodimer composed...
human IL12A is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit ...
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The study aimed to observe the association between IL12A, IL1B and IL17Agene polymorphisms and HBeAg seroconversion in chronic hepatitis B patients who received entecavir treatment.MethodsIL12Ars568408, IL1B rs1143623, and IL17Ars8193036 were genotyped using the MGB-TaqMan SNP genotyping assay in ...