Interleukin 1 (IL-1) receptor€"associated kinase (IRAK)-M is a proximal inhibitor of Toll-like receptor signaling.Methods. To determine the role of IRAK-M in host defense during pneumococcal pneumonia, IRAK-M€" deficient and wild-type mice were intrana...
IL-1 receptor antagonist (IL-1Ra) is a member of the IL-1 family that competitively inhibits the binding of IL-1 to its cell surface receptors, and thus acts as a natural IL-1 inhibitor. Four different IL-1Ra peptides are produced from the same gene by the use of alternative first ex...
IL-1 receptor antagonist (IL-1Ra, gene symbol: Il1rn) is an endogenous inhibitor of IL-1 activity that competes with IL-1α and IL-1β for IL-1R binding. IL-1Ra-deficient (Il1rn−/−) mice spontaneously develop arthritis in an IL-17- and T-cell-dependent manner31,32,33, sugge...
Regulation of the activity of the proinflammatory cytokine IL-1 is complex, involving transcriptional and translational control, precursor processing, a receptor antagonist (IL-1ra), and a decoy receptor. Here we report that the soluble form of the IL-1 receptor accessory protein (AcP) increases ...
Tissue injury and the healing response lead to the release of endogenous danger signals including Toll-like receptor (TLR) and interleukin-1 receptor, type 1 (IL-1R1) ligands, which modulate the immune microenvironment. Because TLRs and IL-1R1 have been shown to influence the repair process of...
别名:Antigen CD121a; CD121 antigen-like family member A; CD121A; CD121a antigen; D2S1473; IL 1; IL 1R 1; IL 1R alpha; IL 1RT1; IL-1R-1; IL-1R-alpha; IL-1RT-1; IL-1RT1; IL1 inhibitor; IL1R; IL1R1; IL1R1_HUMAN; IL1RA; IL1RN; IL1RT1; Interleukin 1 receptor alpha...
IL-1 is regulated by IL-1 receptor antagonist (IL1RA) by competing for binding to ILR1. This control system is consolidated by another potent, specific, and natural IL-1 inhibitor, IL-1 receptor type 2 (IL1R2). This decoy receptor has no signaling properties. It instead counterregulates ...
大鼠糖皮质类固醇受体(GR)ELISA试剂盒 Rat glucocorticoid receptor,GR ELISA试剂盒 大鼠黄体生成素释放激素(LHRH)ELISA试剂盒 Rat Luteinizing Hormone-Releasing Hormone,LHRH ELISA试剂盒 大鼠8异前列腺素(8-iso-PG)ELISA试剂盒 Rat 8-iso prostaglandin,8-iso-PG ELISA试剂盒 大鼠γ干扰素诱导蛋白16/p16(IFI...
Recombinant Horse Interleukin-1 Receptor Antagonist protein(IL1RN) (Active) uniprot号: 规格: ￥620 图像: 基因名称: IL1RN 别名: Interleukin-1 receptor antagonist protein Short name: IL-1RN Short name: IL-1ra Short name: IRAP Alternative name(s): IL1 inhibitor 种属: Equus cab...
Recombinant Mouse Interleukin-1 receptor antagonist protein(Il1rn) (Active)的详细介绍 产品类型: Interleukin 产品名称: uniprot号: 规格: ￥620 图像: 基因名称: Il1rn 别名: IL-1RN, IRAP, IL1 inhibitor 种属: Mus musculus (Mouse) 蛋白描述: ...