The role of IL-6 in the inflammatory and humoral response to adenoviral vectors. J Gene Med. 2000; 2 :194–203.Benihoud K, Salone B, Esselin S, Opolon P, Poli V, Di Giovine M, Perricaudet M, Saggio I. The role of IL-6 in the inflammatory and humoral response to aden...
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IL-6 plays an important role in leukocyte trafficking and the transition from neutrophilic to monocytic infiltration at sites of inflammation.9,10,11 IL-6 trans-signaling promotes leukocyte recruitment to sites of acute inflammation by upregulating endothelial cell (EC) expression of intracellular adhesi...
[6] Botelho, Fernando M., et al. "Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL- 6 in OSM-driven pulmonary inflammation." The Journal of Immunology 191.3 (2013): 1453-1464.[7] Mosley, Bruce, et al. "Dual ...
A. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. J. Leukoc. Biol. 80, 227–236 (2006). CAS PubMed Google Scholar Wolf, J., Rose-John, S. & Garbers, C. Interleukin-6 and its receptors: a highly regulated and dynamic ...
The soluble Interleukin 6 receptor: generation and role in inflammation and cancer. signaling in vivo, and demonstrated that IL-6 trans-signaling is critically involved in generation and maintenance of several inflammatory and autoimmune ... A Chalaris,C Garbers,B Rabe,... - 《European Journal ...
Rheumatoid arthritis (RA) is an autoimmune chronic disease with joint and systemic inflammation and it has been found that interleukin-6 (IL-6) plays a key role in RA. Indeed, various clinical studies have proved that the first-in-class IL-6 inhibitor, tocilizumab, a humanized anti-IL-6 ...