More importantly, loss-of-function mutations of the TRAF3 gene are found at relatively high frequencies in B cell malignancies such as multiple myeloma and B cell lymphoma. Therefore, TRAF3 plays a critical and unique role in B cells to restrain cell survival and differentiation that contributes...
近日,来自耶鲁大学药学院的Andrew Wang 研究团队在Cell上发表了题为Origin and Function of Stress-Induced IL-6 in Murine Models的研究,揭示了应激状态产生的IL-6的主要来源是棕色脂肪组织,并阐明了IL-6水平升高的重要的生理学意义。...
蛋白别名 :B-cell hybridoma growth factor, IL-6, Interleukin HP-1, H-IL-6, ILN, Interleukin, Interleukin6, M-IL-6, R-IL-6, Interleukin-6 UniProt ID(Mouse) P08505 文件和下载 证书 未找到?申请 COA 找到5 个结果 批号 430205-006 ...
Western blot was performed using Anti-IL-6 Monoclonal Antibody (5IL6) (Product # M620) and a 24 kDa band corresponding to IL-6 was observed across to be upregulated upon treatment of HUVEC cells with LPS and Brefeldin A. Whole cell extracts (50 µg lysate) of HUVEC (Lane 1) and ...
IL-6 and disease (4)诊断价值 (5)1980年白介素-6(interleukin 6, IL-6)被Weissenbach发现,命名为β2 干扰素,在之后的研究中IL-6不断被其他人发现并先后命名为杂交瘤/浆细胞瘤生长因子、B 细胞生长因子,肝细胞刺激因子等,直到这些细胞因子的基因被克隆出来后,才命名为IL-6。IL-6是一种多功能细胞...
The control of cell growth and differentiation in B-cell malignancies may be regulated by the autocrine production of cytokines, several of which have been implicated in the growth and survival of B-cells. The effect of interferon-alpha (IFN) therapy in these disorders may be to disrupt autocri...
样本类型Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. 实验时长4.5h实验方法双抗夹心法 规格96T ELISA Kit for Interleukin 6 (IL6) FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
composition of cells, Dilut cell suspension with PBS(PH7.2-7.4), Cell concentration reached 1 million / ml, repeated freeze-thaw cycles, damage cells and release of intracellular components, centrifugation 20-min at the speed of 2000-3000 r.p.m. remove ...
英文名称:IL-6 (B Cell stimulatory factor 2) (HRP) 英文同义词:IL-6 (B Cell stimulatory factor 2) (HRP) CAS号: 分子式: 分子量:0 EINECS号: Mol文件:Mol File IL-6 (B Cell stimulatory factor 2) (HRP) 信息错误报告 提交 按省份浏览IL-6 (B Cell stimulatory factor 2) (HRP)供应商 ...
Thus, Foxj1 restrains B cell activation and the maturation of humoral responses, demonstrating a critical role for at least this forkhead transcription factor in the regulation of B lymphocyte homeostasis. 展开 DOI: 10.4049/jimmunol.175.2.951 被引量: 44 ...