近日，美国华整顿大学医学院Marion Pepper团队在Immunity杂志发表了题为Interleukin-4 downregulates transcription factor BCL6 to promote memory B cell selection in germinal centers的文章。作者发现GCB细胞中的IL-4细胞因子信号通过负向自动调节直接下调转录因子BCL6，从而将细胞从GCB程序中释放并促进MBC的形成，这会...
Cell Mol Immunol. 2009 Dec;6(6):415-22. doi: 10.1038/cmi.2009.53. PMID: 20003817; PMCID: PMC4003035. [17].Hallett MA, Venmar KT, Fingleton B. Cytokine stimulation of epithelial cancer cells: the similar and divergent functions of IL-4 and IL-13. Cancer Res. 2012 Dec 15;72(24):...
近日,美国华整顿大学医学院Marion Pepper团队在Immunity杂志发表了题为Interleukin-4 downregulates transcription factor BCL6 to promote memory B cell selection in germinal centers的文章。作者发现GCB细胞中的IL-4细胞因子信号通过负向自动...
而大多数T细胞亚群,包括耗竭的CD8 T细胞,在Il4敲除肿瘤中富集,并出现富含B细胞和T细胞的淋巴细胞聚集,类似三级淋巴结构。IL-4的缺失导致总CD8 T细胞、PD1+CD4+T细胞和DC细胞的增加。在抗PD-1治疗后,Il4敲除肿瘤中的淋巴细胞聚集显...
功能：IL-5曾补称为T细胞替代因子（Tcellreplacingfactor，TRF），后来发现人类的IL-5对B细胞没有明显...
中文名称: IL-4白介素4抗体含税含运费 英文名称:IL-4 别名:IL4; B cell growth factor 1; B cell IgG differentiation factor; B Cell Stimulatory Factor 1; BCGF 1; BCGF1; Binetrakin; BSF 1; BSF1; HCGF; Hodgk
重组小鼠IL-4由大肠杆菌表达系统产生,并表达编码His23-Ser140的靶基因。Interleukin-4;B-cell IgG differentiation factor;B-cell growth factor 1;B-cell stimulatory factor 1;IGG1 induction factor;Lymphocyte stimulatory factor 1;IL-4;BSF-1 分子量 13.4 KDa 表观分子量 14 KDa(还原条件下) 供货形式 ...
Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13 kDa ‑ 18 kDa Th2 cytokine that shows pleiotropic effects during immune responses (1‑3). It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundle...
产品货号 产品规格 目录价 数量 90169ES08 5μg 815.00 90169ES60 100 μg 8515.00 90169ES76 500 μg 22115.00 批量采购,请点击询价 下载产品说明书 产品说明书 FAQ COA 已发表文献 Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a pleiotropic cytokine that induces differentiatio...