IL-4 基因概述 IL4 gene / cDNA is a protein-coding gene which located on 5q31.1. The IL4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.133 organisms have orthologs with human gene IL4. All IL-4 genes IL-4 基因功能 The protein encoded by this gene is...
CD3 signaling leads to an early induction of NFAT1-P1 complexes correlating with a strong induction of the IL-4 gene. In later phases of CD3 activation, P1 is also bound by Stat6 and a fall in the IL-4 mRNA levels takes place. These two late events during CD3 activation were found ...
Qiu LJ, Ni J, Cen H, Wen PF, Zhang M, Liang Y, Pan HF, Mao C, Ye DQ. Relationship between the IL-4 gene promoter -590C/T (rs2243250) polymorphism and susceptibility to autoimmune diseases: a meta-analysis. J Eur Acad Dermatol Venereol 2015; 29:48-55...
Retroviral-mediated IL-4 gene therapy in spon- taneous adenocarcinomas from MMTV-neu transgenic mice. Gene Therapy 1999; 6: 1893-1897.Sacco M, Benedetti S, Cato EM, Caniatti M, Ceruti R, Scanziani E, et al. Retrovirus-mediated IL-4 gene therapy in spontaneous adenocarcinomas from MMTV-neu...
2) Interleukin-4 gene il-4基因 1. Interleukin-4 gene is transformed into Zhong Gan 11 cabbage (Brassica oleracea L. 试验结果表明:il-4基因对带1~2mm子叶柄的子叶的转化率显著高于下胚轴;带柄子叶在预培养1d、侵染3min、共培养1d时,转化效果最好,转化率达23。 更多例句>> ...
il -4基因的骨髓间充质干细胞对豚鼠免疫性内耳病基因治疗的研究 gene therapy of inner ear injection with bone -marrow mesenchymal stem cells decorated with interleukin-4 gene on immune-mediated inner ear disease in guinea pigs 下载文档 收藏 打印 转格式 il...
Acute expression of the IL4 gene by differentiated TH2 cells is regulated by many positive and negative inducible transcription factors, such as nuclear factor of activated T cells (NFAT) proteins, AP1, nuclear factor-κB, interferon regulatory factor 1 (IRF1) and other factors that bind the pr...
Although allele distribution of IL-4 gene showed significant difference considering histopathological grades in both smoking and total patients group, allele distribution of IL-1RN and TNF-尾 was not different. Conclusion: The present research suggests that the IL-1RN and IL-4 gene polymorphisms ...
( 1992 ). Interleukin 4 (IL) 4 up-regulates gene and surface IL 1 receptor type I in murine T helper type 2 cells . Eur. J. Immunol. , 22 , 153 – 157 .Koch K C, Ye K, Clark B D, Dinarello C A. 1992. Interleukin-4 (IL-4) up-regulates gene and surface IL-1 receptor...
We analyzed functions of BCL6 in chromatin remodeling of IL-4 gene by chromatin immuno precipitation (Chip) assay for Thl and Th2 cells. We discovered BCL6-binding sites near the DNase hypersensitive sites around IL-4 gene, and that BCL6 is involved in chromatin remodeling through regulation ...