IL-2 Receptor (IL-2R) Alpha, Beta, and Gamma Chains Expressed on Blasts of Acute Myelocytic Leukemia May Not Be FunctionalPreliminary clinical studies including IL-2 in chemotherapeutic strategies for treatment of acute myelocytic leukemia suggest that IL-2 may improve the overall outcome of the ...
et al. Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA’s. Science 244, 551–556 (1989). Article CAS PubMed Google Scholar Takeshita, T. et al. Cloning of the gamma chain of the human IL-2 receptor. Science 257, ...
在这里IL-2受体是另一个关键。IL-2 receptor (IL-2R) 是由三条链组成的复合物，α链 (IL-2 R alpha，CD25)，β链 (IL-2 R beta，CD122) 和通用γ链 (IL-2 R gamma，CD132)，其中，γ链由IL-2家族成员共享 (IL-4, IL-7, IL-9, IL-15和IL-21)。IL-2受体IL-2 R alpha以低亲和力结合I...
在这里IL-2受体是另一个关键。IL-2 receptor (IL-2R) 是由三条链组成的复合物,α链 (IL-2 R alpha,CD25),β链 (IL-2 R beta,CD122) 和通用γ链 (IL-2 R gamma,CD132),其中,γ链由IL-2家族成员共享 (IL-4, IL-7, IL-9, IL-15和IL-21)。IL-2受体IL-2 R alpha以低亲和力结合IL-2,...
Analysis of IL-15 interaction with subunits of the IL-2 receptor (IL-2R) revealed that the alpha subunit was not involved in IL-15 binding. We demonstrated directly in cells transfected with IL-2R subunits that both the beta and gamma chains are required for IL-15 binding and signaling....
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-...
RNA was used to build libraries with the QIAseq Immune Repertoire T-cell Receptor Panel (Catalog 333,705-IMHS-001Z). With this kit, RNA is reverse transcribed with a pool of gene-specific primers against the C (constant) region for the T cell receptor alpha, beta, gamma, and delta ...
During T-cell development in thymus, CD25, the IL-2 receptor alpha chain (IL-2Ralpha) is already expressed in early double-negative (DN) thymocytes where c... Yeh,J.-H. - 《Nucleic Acids Research》 被引量: 83发表: 2002年 T cell receptor ligation induces interleukin (IL) 2R beta ch...
中文名称:IL-2R gamma 白介素2受体γ链抗体英文名称:IL-2R gamma 品牌:沪震生物产地:中国/上海 保存条件:-20°C纯度规格:> 99% 产品类别:抗体 一抗 抗体名:IL2 Receptor gamma; IL2R gamma; IL 2R gamma; IL-2 receptor gamma precursor; IL2 Receptor gamma; CD132; CD 132; common cytokine recept...
Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL2 shares 56% ...