此外,某些神经元表达IL-4Rα和IL-13Rα1,表明存在神经免疫联系。IL-13Rα2在非造血细胞中表达,并在某些癌细胞上过度表达;其在特应性疾病中的作用尚未得到充分探讨。 "Commonality of the IL-4/IL-13 pathway in atopic diseases." Expert Rev Clin Immu***,2007. 13(5): 425-437. ...
The COVID-19 fatality rate is high when compared to the H1N1pdm09 (pandemic Influenza A virus H1N1 subtype) rate, and although both cause an aggravated inflammatory response, the differences in the mechanisms of both pandemic pneumonias need clarification. Thus, our goal was to analyze tissue ...
小鼠白介素13(IL13)检测试剂盒相关产品如下:hz-E10073 中文名称:人组织因子途径抑制物(TFPI)ELISA试剂盒 英文名称:Human Tissue factor pathway inhibitor,TFPI ELISAkit 规格:48T/96Thz-E10074 中文名称:人干扰素诱导蛋白10(IP-10/CXCL10)ELISA试剂盒 英文名称:Human interferon-inducible protein 10,IP-10 ELIS...
Polymorphisms in IL-4/ IL-13 pathway genes and glioma risk: An updated meta-analysis. Tumour Biol 2015; 36(1): 121-7.CHEN P Q, CHEN C, CHEN K, et al. Polymor- phisms in IL-4/IL-13 pathway genes and glioma risk: an updated meta-analysis [J]. Tumor Biol, 2014, 36 (1):...
et al. A TNFRSF14-FcvarepsilonRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice. Nat. Commun. 7, 13696 (2016). Article ADS CAS PubMed PubMed Central Google Scholar Glaab, T., Taube, C., Braun, A. & Mitzner, W. Invasive and non...
Resveratrol is a polyphenolic compound showing anti-inflammatory activity by inhibition of high mobility group box 1 cytokine responsible for the activation of nuclear factor-κB pathway in atopic dermatitis. To evaluate the efficacy of resveratrol through topical route we have developed resveratrol-loaded...
IL-13 induces production of IGF-1 by activating Jak/Stat signaling pathway in vitro IL-13 can bind with a heterodimeric receptor composed of IL-4Rα and IL-13Rα1 or with IL-13Rα2 [45]. IL-13Rα2 is not believed to contribute to IL-13 signaling since it possesses a short cytopl...
Role of IL-13,PGE2 and PGI2 for participating in hepatic fibrosis by activating hepatic stellate cells through PKC pathway 在线阅读 下载PDF 引用 收藏 分享 摘要 目的研究白介素-13(IL-13)、前列腺素E2(PGE2)和前列环素(PGI2)在肝星形细胞(HSCs)参与肝脏纤维化中的作用。方法通过酶联免疫吸附试验(...
Prenatal oxidative balance might influence cord blood IgE (cIgE) levels. We aimed to explore if certain prenatal dietary sources of antioxidants and pro-oxidants are associated with cIgE elevation and if they interact with IL4 and IL13 pathway genes. A s
IL-4Rα is a receptor subunit shared byIL-4and IL-13, and the development of IL-4Rα-targeted therapies aims to block IL-4 and IL-13 binding to the receptor. This inhibition effectively disrupts the signaling pathway mediated by IL-4 and IL-13, presenting an innovative mechanism known ...