[6] Botelho, Fernando M., et al. "Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL- 6 in OSM-driven pulmonary inflammation." The Journal of Immunology 191.3 (2013): 1453-1464. [7] Mosley, Bruce, et al. "Dual o...
英文名称:Monoclonal Antibody to Interleukin 6 (IL6) 分子式:电询 纯度:100 % 产地:进口/国产 品牌:钰博生物 包装规格:0.1ml/0.2ml 别名:电询 白介素6(IL6)单克隆抗体 Organism Species: Homo sapiens (Human) Instruction manual FOR IN VITRO USE AND RESEARCH USE ONLY ...
Utilize our IL-6 antibodies in your research endeavors for dependable IL-6 detection.recommended IL-6 antibody (AA 111-150) (ABIN728083) IL6 Reactivity: Human, Mouse, Rat, Rabbit, Cow WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated ...
Part of the book series: Contemporary Immunology ((CONTIM)) 468 Accesses Summary Interleukin-6 (IL-6) is a pleiotropic cytokine thought to play important regulatory roles in immunity, hemopoiesis, and inflammation (reviewed in ref. 1). The generation of IL-6-deficient mice by gene targeting...
Journal of Clinical ImmunologySzabo G, Kodys K, Miller-Graziano CL. Elevated monocyte interleukin-6 (IL-6) production in immunosuppressed trauma patients. I. Role of Fc gamma RI cross-linking stimulation. J Clin Immunol 1991;11:326-35.
Members of the suppressor of cytokine signaling (SOCS) family are potentially key physiological negative regulators of interleukin-6 (IL-6) signaling. To examine whether SOCS3 is involved in regulating this signaling, we have used conditional gene target
A. IL-6 as a keystone cytokine in health and disease. Nat. Immunol. 16, 448–457 (2015). CAS PubMed Google Scholar Johnson, D. E., O’Keefe, R. A. & Grandis, J. R. Targeting the IL-6/JAK/STAT3 signalling axis in cancer. Nat. Rev. Clin. Oncol. 15, 234–248 (2018). ...
首先,分子定义不明确。在体内,6-PEG-BEMPEG是一种无活性的前药,通过水解释放PEG链逐步释放活性,只有1-PEG和2-PEG形式具有活性。此外,CD122偏向性不足。第三,黑色素瘤是一种高度免疫原性的肿瘤,已有研究表明其对检查点抑制剂的高反应率,因此联合IL-2可能没有...
Our data indicated that the LAT–PLCγ1 interaction is important for controlling IL-6 production by T cells and demonstrated a critical role of IL-6 in the development of this lymphoproliferative syndrome.Issue Section: Molecular and Structural Immunology ...
细胞系THP-1,并随机分为过表达组、空白组、模型组、对照组;过表达组和空白组分别转染P2X7R过表达质粒、空白载体质粒,转染5 d,将过表达组、空白组、模型组THP-1细胞用100 ng/mL的PMA刺激3 h后分化为巨噬细胞,另将MSU晶体用氢...