P<0.001).The study of cytokine levels secreted by ILC2 recruited from abdominal cavity showed that the levels of IL⁃9 and IL⁃13 secreted by ILC2 in abdominal cavity increased markedly at 12 h postoperatively and ...
中文别名:IL-1 Receptor Type 2蛋白; IL-1R-2蛋白 来源:Human Cells 纯度:Greater than 95% as determined by reducing SDS-PAGE. 内毒素水平:Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 形态:Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. ...
IL-2 was first identified as a growth factor capable of driving the expansion of activated human T cell populations. In the more than 40 years since its discovery, a tremendous amount has been learned regarding the mechanisms that regulate the expression
The first step in mounting an antifungal immune response is the recognition of extracellular pathogen-associated molecular patterns (PAMPs) of invading organism, such as Candida albicans, by soluble and membrane-bound pattern recognition receptors (PRRs)1,2. Following recognition, the effective control ...
5. Heinrich PC, Behrmann I, Muller-Newen G, et al. 1998. Biochem J. 334 ( Pt 2):297-314. BackgroundInterleukin-6 (IL-6) is an interleukin that in humans is encoded by the IL-6 gene and acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells...
1.2.2不同剂量LPS、TNF-α、IL-1β诱导RAW264.7细胞分泌NO的比较取刚刚长成完整单层的RAW264.7细胞一瓶,胰蛋白酶消化后吹打细胞,调整细胞数目至2×105 cell/mL。于96孔细胞培养板中每孔加入100 μL细胞悬液,置于CO2培养箱中继续培养12 h。取出培养板后吸掉原培养液,每孔加入190 μL无血清培养液。6 h后加入...
我们总 结了 1W I1在机体中的免疫调节作用及机制，以期为感染、肿瘤和自身免疫性疾病的治疗提供新思路。[关键词]白细胞介素4诱导蛋白1(I L4I1);免疫调节；肿瘤免疫逃逸；自身免疫性疾病；髓鞘再生；综述 [中图分类号]R392. 9, R392.l l，R593. 2, G353.ll [文献标志码]A The role of IL4I1 in...
In contrast, IL-2 and type 2 cytokines (including IL-5 and IL-13) were secreted at equivalent levels in the 2 groups. We hypothesized that impaired IL-21 secretion by IL-12Rβ1–>deficient cells was, at least partially, due to their inability to respond to IL-12 secreted by antigen-...
cytokine multiplex assay: A) interleukin (IL) 1 alpha (IL-1α); B) IL-2; C) IL-4; D) IL-6; E) granulocyte-macrophage colony-stimulating factor (GMCSF); F) macrophage inflammatory protein-1A (MIF-1A); or G) regulated on activation, normal T cell expressed and secreted (RANTES). ...
This study analyzed the soluble factors secreted by lung cancer cells, which are responsible for increasing osteoclast differentiation. Addition of recombinant human interleukin-8 (rhIL-8), present in large amounts in A549-conditioned medium (CM) and NCI-H460-CM, mimicked the inductive effect of...