下表中整理了IL-2在肿瘤和自身免疫领域的应用,这里就不做翻译了,相信大家更愿意去读读原文《Engineering IL-2 to Give NewLife to T Cell Immunotherapy》。偷懒的话就关注下公众号,回复:“ IL2 ”下载。 资源: 后台回复:2020,即得Top 200 SMALL Molecul...
东抗生物细胞培养蛋白产品原料白介素2(IL-2 )已获得DMF DMF备案号:040170 查询网址:https://www.fda.gov/drugs/forms-submission-requirements/drug-master-files-dmfs(第三季度后可查) 此外,东抗生物多种产品在DMF备案进行中,敬请期待! 什么是DMF?...
2. Analysis by RP-HPLC, using a calibrated solution of IL-2 as a Reference Standard. Usage: Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. Warning: file(...
近日，《Drugs》杂志刊登了恒瑞医药创新药夫那奇珠单抗（安达静®）的文章《Vunakizumab：First Approval》[1]。《Drugs》杂志作为药学-毒理学领域的顶级1区期刊，聚焦于该领域的重点研究和前沿进展，杂志最新影响因子达到了13。这是继Ⅱ期、Ⅲ期临床试验文章后，夫那奇珠单抗相关研究成果再一次刊登于国际顶级期刊。
1.SudheerK.Vuyyuru,LisaM.Shackelton,JurijHanzel,ChristopherMa,VipulJairath,BrianG.Feagan,TargetingIL‑23forIBD:RationaleandProgresstoDate,Drugs(2023)83:873–891 2.YvanJamilloux,yvan.jamilloux@chu-lyon.fr,ThomasElJammal,LucineVuitton,JAKinhibitorsforthetreatmentofautoimmuneandinflammatorydiseases,Autoimmun...
Renal and hepatic function istypically impaired during therapy with aldesleukin, so interactionwith other drugs that undergo elimination by these organsis possible. Biochem/physiol Actions Interleukin-2 (IL-2) is an immunomodulatory factor produced by certain subsets of T lymphocytes. This lymphokine...
近日,《Drugs》杂志刊登了恒瑞医药创新药夫那奇珠单抗(安达静®)的文章《Vunakizumab:First Approval》[1]。《Drugs》杂志作为药学-毒理学领域的顶级1区期刊,聚焦于该领域的重点研究和前沿进展,杂志最新影响因子达到了13。这是继Ⅱ期、Ⅲ期临床试验文章后,夫那奇珠单抗相关研究成果再一次刊登于国际顶级期刊。此次...
AS的治疗包括非药物治疗、药物治疗和外科治疗。非甾体抗炎药(Non-steroidal anti-inflammatory drugs,NSAIDs)是治疗AS的一线药物,对NSAIDs治疗后病情仍活动或者不耐受的AS患者,推荐使用生物制剂类药物[2]。然而仍有部分活动性AS患者治疗效果欠佳。 关于夫那奇珠单抗注射液(SHR-1314)...
[5]Magrey M,et al.Drugs Real World Outcomes. 2019 Jun;6(2):83-91. [6]Schett G, et al. EULAR 2019. #FRI0380. [7]Baraliakos X,et al.RMD Open.2019 Sep 3;5(2): e001005. [8]Braun J,et al.Ann Rheum Dis.2017 Jun;76(6): 1070-1077. ...
of their suppressive activity. In this review, we summarise the role of IL-2 in Tregbiology and consequences of dysfunctional IL-2 signalling pathways. We then examine evidence of efficacy of IL-2-based biological drugs targeting Tregwith specific focus on therapeutic candidates in clinical trials...