il-17 signaling pathway翻译 il-17signalingpathway翻译：IL-17信号通路
翻译:北医三院刘佩玲 摘要:白介素17(IL-17)和低氧已被认为在类风湿关节炎(RA)中起着关键作用。在该研究中,在RANKL和M-CSF存在下,IL-17和氯化钴(CoCl2)(一种缺氧模拟物)的联合处理显著增加了破骨细胞形成以及RAW 264.7巨噬细胞中TRAP和MMP-9的表达。IL-17和CoCl2的统一作用通过RANKL/NF-κB/NFATc1信号通路...
IL-17RA是一种常见的受体,与IL-17RB、IL-17RC和IL-17RE结合形成异二聚体复合物。到目前为止,所有的IL-17受体都募集Act1作为下游信号的衔接分子。IL-17A和IL-17F通过IL-17RA-RC复合物发出信号,触发TRAF6依赖型靶基因转录和TRAF6非依赖型、IKKi依赖的mRNA稳定,这两者对宿主防御具有重要意义,同时也与自身免疫...
IL 17 Signaling Pathway Inflammation is a complex response involving many different cells and signaling molecules, including the secretion of the cytokine IL-17 by activated T cells. IL-17 secretion is restricted to specific subsets of T cells but the receptor for IL-17 is widely expressed throug...
IL-17 signaling pathway The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial roles in both acute and chronic inflammatory responses. IL-17A, the hallmark cytokine of the newly defined T helper 17 (TH17) cell subset, has important roles in protectin...
Altogether our results emphasize the role of the IL-17B/IL-17RB signaling pathway in breast tumors and identify IL-17B and its receptor as attractive ... E Laprevotte,S Cochaud,SD Manoir,... - 《Oncotarget》 被引量: 2发表: 2017年 Effect of pulmonary infection on TLR7/IL-23/IL-17 ...
To analyze the clinical significance of Toll-Like Receptor 7/Interleukin-23/Interleukin-17 (TLR7/IL-23/IL-17) signaling pathway in patients with Acute Respiratory Distress Syndrome (ARDS). Method The clinical data of 85 patients with ARDS were retrospectively analyzed and set as the ARDS group,...
结论黄芪甲苷可能通过抑制IL-23/IL-17信号通路发挥抗VMC作用,且具有剂量依赖性。关键词:黄芪甲苷;病毒性心肌炎;白介素-23;白介素-17InhibitionofviralmyocarditisbyAstragalosidethroughIL-23/IL-17signalingpathwayLIUDanli,LIUHaiying,GAOShunli(DepartmentofPediatrics,TheFirstAffiliatedHospital,UniversityofSouthChina,...
[12].Karo-Atar D, Bitton A, Benhar I, Munitz A. Therapeutic Targeting of the Interleukin-4/Interleukin-13 Signaling Pathway: In Allergy and Beyond. BioDrugs. 2018 Jun;32(3):201-220. doi: 10.1007/s40259-018-0280-7. PMID: 29736903. ...