肠道微生物代谢物靶向 JUN 抑制肾细胞癌:基于 IL-17 信号通路的网络药理学新探索 《Molecular Diversity》:Gut microbial metabolites targeting JUN in renal cell carcinoma via IL-17 signaling pathway: network pharmacology approach 编辑推荐: 肾细胞
结论 IL-17 信号通路在回归热疏螺旋体感染诱导的中枢神经系 统疾病中起重要作用 。[ 关键词 ] IL-17 信号通路 ; 回归热 ; 疏螺旋体 ; 神经症状冲图分类号 ] R514.1 [ 文献标识码 ] A [ 文章编号 ] 1673-7210(2021)04(a)-0004-05Roles of IL-17 signaling pathway in the development of relapsing...
图摘 标题:Supplementary Hesperidin Alleviated CPT-11-Induced Diarrhea by Modulating Gut Microbiota and Inhibiting the IL-17 Signaling Pathway / 补充橙皮苷通过调节肠道微生物群和抑制IL-17信号通路减…
13 Mechanism of astragaloside IV alleviating DCM in mice by regulating IL-17 signaling pathway 综上,本研究表明黄芪甲苷可以改善 DCM 小 鼠心功能,其作用机制可能与黄芪甲苷抑制 IL-17 信号通路相关.本研究为 DCM 的临床防治奠定了 基础,为研发针对 DCM 的新的有效药物提供理论 依据.但黄芪甲苷不同剂量对...
mediate an alternative pathway for autonomous activation of IL-17R signaling, targeting which could be a therapeutic option for IL-17-related diseases in addition to current antibody therapies. 编辑:胡肖希 美编:王乐 审核:辛...
3.防己地黄汤作用IL-17信号通路。 7.参考文献 ZHAO Wenting, JIANG Honghong, GU Yunfan, et al. Fangji Dihuang formulation ameliorated DNCB-induced atopic dermatitis-like skin lesions by IL-17 signaling pathway: integrating network analysis and experimental validation [J]. Frontiers in Pharmacology, 20...
The interleukin-17 (IL-17) signaling pathway is intricately linked with immunity and inflammation; however, the association between the IL-17 signaling pathway and skeletal muscle inflammation remains poorly understood. The study aims to investigate the role of the IL-17 signaling pathway in skeletal...
gren's Disease-like Animals via Regulation of the IL-17RA Signaling Pathway 编辑推荐: 本研究针对干燥综合征(SjD)中唾液腺功能障碍的临床难题,揭示了SHP2通过IL-17RA/ACT1/TRAF6信号轴加剧炎症和细胞凋亡的新机制。武汉大学团队采用SHP2变构抑制剂SHP099干预SjD样动物模型,证实其可显著改善唾液腺病理损伤、...
结论:MHCD可下调IgAN模型大鼠IL-17信号通路相关因子的表达,改善血瘀状态,减轻肾脏病理损伤。 文献来源: Ma S, Yang B, Zhao M, et al. Effects of modified Huangqi Chifeng decoction on the IL-17 signaling pathway in an IgA...