2.防己地黄汤抑制TH1、Th2、Th17细胞以及细胞因子IL-4 、 IFN-γ、IL-17的基因。 3.防己地黄汤作用IL-17信号通路。 7.参考文献 ZHAO Wenting, JIANG Honghong, GU Yunfan, et al. Fangji Dihuang formulation ameliorated DNCB-induced atopic dermatitis-like skin lesions by IL-17 signaling pathway: integr...
17细胞、IL-17的 发现作了历史性回顾,并综述了IL-17受体介导的信号传导途径和生理功能的研究进展,为T H 17细 胞、IL-17及其受体作为药物治疗的新靶点提供新思路。 关键词白介素17(IL-17);T H 17细胞;宿主防御;自身免疫 国家自然科学资金(No.30930084,No.30871298),中国科学院百人 ...
IL-17的信号传导及功能研究
IL-17A诱导的转录因子(如C/EBPδ)可抑制炎症基因的表达。通过IL-17RA-RB受体复合物,IL-17E(IL-25)信号激活MAPK和NFκB通路用以诱导Th2反应。IL-17C通过IL-17RA-RE复合物传递信号。IL-17B已被证明与IL-17RB相互作用。IL-17D的受体未知。IL-17B、IL-17C和IL-17D的生物学功能尚不清楚。
il-17 signaling pathway翻译 il-17signalingpathway翻译：IL-17信号通路
IL-17 signaling pathway has an ethnicity-specific effect in LSCC where it is upregulated in the Chinese while not in the Caucasians and IL17RC might play a key role. Targeting genes located in the IL-17 signaling pathway may be beneficial for Chinese LSCC patients. 展开 关键词: IL-17 ...
IL-17 signaling pathway The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial roles in both acute and chronic inflammatory responses. IL-17A, the hallmark cytokine of the newly defined T helper 17 (TH17) cell subset, has important roles in protectin...
黄芪甲苷可能通过抑制IL-23/IL一17信号通路发挥抗VMC作用,且具有剂量依赖性。 关键词:黄芪甲苷;病毒性心肌炎; 白介素-23; 白介素一17 InhibitionofviralmyoearditisbyAstragalosidethroughIL-23/IL-17signalingpathway LIUDanli,LIUHaiying, GAOShunli(DepartmentofPediatrics,TheFirstAffiliatedHospitaLUniversityofSouthCh...
IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer progressiondoi:10.1016/j.gendis.2024.101489Yihong WeiDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, ChinaYing XuEye Hospital of Shandong First Medical University, Jinan, Shandong 250012, ...
for the first time, that IL-17 modulates RANKL expression of osteoblasts through an autophagy-JAK2-STAT3 signaling pathway, thus affecting bone metabolism.do... Wang, ZhongxiuWei, YingmingLei, LihongZhong, JiahuiShen, YeqiTan, JingyiXia, MengjiaoWu, YanminSun, WeilianChen, Lili - 《Connective ...