il-17 signaling pathway翻译 il-17signalingpathway翻译：IL-17信号通路
IL-17 signaling pathway The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial roles in both acute and chronic inflammatory responses. IL-17A, the hallmark cytokine of the newly defined T helper 17 (TH17) cell subset, has important roles in protectin...
IL-17RA是一种常见的受体,与IL-17RB、IL-17RC和IL-17RE结合形成异二聚体复合物。到目前为止,所有的IL-17受体都募集Act1作为下游信号的衔接分子。IL-17A和IL-17F通过IL-17RA-RC复合物发出信号,触发TRAF6依赖型靶基因转录和TRAF6非依赖型、IKKi依赖的mRNA稳定,这两者对宿主防御具有重要意义,同时也与自身免疫...
IL 17 Signaling Pathway Inflammation is a complex response involving many different cells and signaling molecules, including the secretion of the cytokine IL-17 by activated T cells. IL-17 secretion is restricted to specific subsets of T cells but the receptor for IL-17 is widely expressed throug...
Mechanism of IL-17 Signaling Pathway in Spleen Inflammatory Response Induced by Altitude Hypoxia in Mice 引用 收藏 分享 摘要 目的探究高原低氧环境诱导小鼠脾脏组织炎症反应发生的作用机制。方法将C57BL/6小鼠随机分为平原常氧组和高原低氧组,每组5只。其中,平原常氧组饲养于海拔400 m(氧浓度19.88%)常氧浓度...
Figure 1. IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer (DTC) progression. (A) The volcano plot of differentially expressed genes (DEGs) in DTCs. (B) Co-expression of DEGs in DTCs was detected by Venn diagram. (C) Protein-protein interaction analysis of common...
Increased expression of the p-STAT3/IL-17 signaling pathway in patients with dermatomyositis 来自 掌桥科研 喜欢 0 阅读量: 6 作者: D Li,W Jia,Zhou LHao YWang KYang BYang JLuo DFu Z. 摘要: Objectives: The aim is to explore the roles of phosphorylated signal transduction and activator of...
This comprehensive review details the recognition of activity, signaling, and the roles of IL17B-IL17RB in breast cancer have caused to determination of new therapeutic mechanisms with the purpose of introduction this system and the regulation of its signaling pathway. 展开 关键词:...
黄芪甲苷可能通过抑制IL-23/IL-17信号通路发挥抗VMC作用,且具有剂量依赖性。 关键词:黄芪甲苷;病毒性心肌炎;白介素-23;白介素-17 InhibitionofviralmyocarditisbyAstragalosidethroughIL-23/IL-17signalingpathwayLIUDanli,LIUHaiying, GAOShunli(DepartmentofPediatrics,TheFirstAffiliatedHospital,UniversityofSouthChina,He...
【摘要】辅助性T细胞17(Th17)是一种新型T细胞亚群,能够分泌产生重要效应因子IL-17,IL-17作为炎症介质结合细胞上的IL-17受体引发包括NF-κB、MAPK等途径在内的一系列信号传递而发挥其生物学功能,介导炎症、感染等的发生和发展.自身免疫性疾病是由于机体免疫功能紊乱,对自身抗原发生免疫反应,进而导致自身机体损伤的一种...