13 Mechanism of astragaloside IV alleviating DCM in mice by regulating IL-17 signaling pathway 综上,本研究表明黄芪甲苷可以改善 DCM 小 鼠心功能,其作用机制可能与黄芪甲苷抑制 IL-17 信号通路相关.本研究为 DCM 的临床防治奠定了 基础,为研发针对 DCM 的新的有效药物提供理论 依据.但黄芪甲苷不同剂量对...
7.参考文献 ZHAO Wenting, JIANG Honghong, GU Yunfan, et al. Fangji Dihuang formulation ameliorated DNCB-induced atopic dermatitis-like skin lesions by IL-17 signaling pathway: integrating network analysis and experimentalvalidation[J]. Frontiers in Pharmacology, 2023, 14: 1220945. 姜红红. 防己地黄...
发现作了历史性回顾,并综述了IL-17受体介导的信号传导途径和生理功能的研究进展,为T H 17细 胞、IL-17及其受体作为药物治疗的新靶点提供新思路。 关键词白介素17(IL-17);T H 17细胞;宿主防御;自身免疫 国家自然科学资金(No.30930084,No.30871298),中国科学院百人 ...
IL-17的信号传导及功能研究
hibiting IL-23/IL-17 signaling pathway. Key words: Astragaloside; viral myocarditis; interleukin-23; interleukin-17 病毒性心肌炎(viral myocarditis,VMC)是由柯萨 奇病毒B3 (Coxsackievirus B3,CVB3)等病毒侵犯心肌, doi:10.3969 / j.issn.1000-3606.2014.06.018 ·论著· 基金项目:衡阳市科技局科研课题(No...
intheproliferationandmetastasisofgastriccancerandthemechanismofactioninangiogenesis,providingnewideasfortheindepthstudyoftheroleofIL17anditsrelatedsignalingpathwaysintheoccurrenceanddevelopmentofgastriccancerandtheclinicaldiagnosisandtreatmentofgastriccancer. [Keywords]gastriccancer;inflammatoryimmunity;IL17;signalingpathway...
IL-17A诱导的转录因子(如C/EBPδ)可抑制炎症基因的表达。通过IL-17RA-RB受体复合物,IL-17E(IL-25)信号激活MAPK和NFκB通路用以诱导Th2反应。IL-17C通过IL-17RA-RE复合物传递信号。IL-17B已被证明与IL-17RB相互作用。IL-17D的受体未知。IL-17B、IL-17C和IL-17D的生物学功能尚不清楚。
Figure 1. IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer (DTC) progression. (A) The volcano plot of differentially expressed genes (DEGs) in DTCs. (B) Co-expression of DEGs in DTCs was detected by Venn diagram. (C) Protein-protein interaction analysis of common...
il-17 signaling pathway翻译 il-17signalingpathway翻译：IL-17信号通路
IL-17 signaling pathway The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial roles in both acute and chronic inflammatory responses. IL-17A, the hallmark cytokine of the newly defined T helper 17 (TH17) cell subset, has important roles in protectin...