IGH and IGK gene rearrangements as PCR targets for pediatric Burkitt's lymphoma and mature B-ALL MRD analysis. Lab Invest 2009; 89: 1182-86.Lovisa F, Mussolin L, Corral L, Pillon M, Cazzaniga G, Biondi A, et al. IGH and IGK gene rearrangements as PCR targets for pediatric Burkitt’s...
We also pointed to the presence of multiple clones as a likely cause of MP-IGH detection even in cases with an immunophenotypically monoclonal disease, on the basis of IGK, IGL and incomplete IGH gene rearrangement analyses. Still, the underlying biological cause of MP-IGHs possibly involves ...
7、tly useful to solve the problems in differentiating diagnosis of elusive proliferative lesions of lymph tissue, by IgH, TCR gene rearrangement analysis.Key words:Lymphoma; Gene rearrangement; Diagnosis0 引言 本研究应用IgH、TCR、TCR基因重排技术对36例疑难淋巴组织增生性病变进行分析,以探讨实际工作中解...
Ig H and L chain variable region gene sequence analysis of twelve synovial tissue-derived B cell lines pro- ducing IgA, IgG, and IgM rheumatoid factors structure/function com- parisons of antigenic specificity, V gene sequence, and IG isotype. Autoimmunity 1995; 22:229-43....
sults:There was significantly different in the copy number changes of IgH gene rearrangement between before and after combinated chemotherapy P < . 5). o lus o s:The copy number of IgH gene rearrangement after combined chemotherapy was significantly lower than before.It can be used for evaluatio...
PCR-based clonality analysis of B-cell lymphomas in paraffin-embedded tissues: diagnostic value of immunoglobulin kappa and lambda light chain gene rearrangement investigation[J]. Pathol Res Pract, 2006,202(6):425-431. 返回引文位置Google Scholar 百度学术 万方数据 [2] 褚俊锋,刘艳艳,赵燕,等. ...
[1]Garcia MJ, Martines-Delgado B,Granizo JJ,et al.IgH,TCR-gamma,and TCR-beta gene rearrangement in 80 B- and T-cell non-Hodgkin’s lymphomas:study of the association between proliferation and the so-called ‘aberrant’ patterns.Diagn mol Pathol,...
cases negative for clonal rearrangement, 4 were reactive proliferation,2 Cat scratch lymphadenitis and 1 atypical proliferation.Conclusion It is significantly useful to solve the problems in differentiating diagnosis of elusive proliferative lesions of lymph tissue, by IgH, TCR gene rearrangement analysis....
Sequences were aligned to ImMunoGeneTics sequence directory using the IMGT V-QUEST analysis software. Results. A complete productive monoclonal IGHV-D-J rearrangement was obtained in 84/107 cases (78%). Using a homology cut-off value of 98% to the nearest germline gene, we observed mutated ...
1. Study of IgH gene rearrangement in B-NHL before and after chemical therapy; 化疗前后B-NHL淋巴瘤IgH基因重排变化的研究2. Results Eleven of 16 cases expressed IgH gene rearrangement, 4 cases did TCRγ gene rearrangement, and one expressed neither IgH and TCRγ gene rearrangement. 方法 ...