IgG4-related disease. N Engl J Med. 2012; 366 :539–551.John HS, Yoh Z, Vikram D. IgG4-related disease. N Engl J Med. 2012; 366 :539–551. doi: 10.1056/NEJMra1104650. [ Cross Ref ]Stone JH, Zen Y, Deshpande V. IgG4-related disease . N Engl J Med (2012) 366 ( 6 ):...
IgG4相关性疾病(IgG4 related disease,IgG4-RD)是一种由IgG4淋巴细胞介导的、累及多器官、多系统的慢性进行性自身免疫性疾病。其特点是组织器官中IgG4阳性浆细胞浸润多灶性纤维硬化性改变 [ 1 ]。目前报道中累及心血管系统的不多,主要有主动脉炎、动脉炎、炎性动脉瘤及动脉周围炎等中大动脉表现 [ 2 , 3 ...
International Consensus Guidance Statement on the Management and Treatment of IgG4-Related Disease[J]. Arthritis Rheumatol, 2015,67(7):1688-1699. DOI: 10.1002/art.39132 . 返回引文位置Google Scholar 百度学术 万方数据 8 Völker HU , Scheich M , Zettl A ,et al. Laryngeal inflammatory ...
IgG4-related disease (IgG4RD) is a novel clinical disease entity characterized by elevated serum IgG4 concentration and tumefaction or tissue infiltration ... Hisanori,Umehara,Kazuichi,... - 《Modern Rheumatology》 被引量: 736发表: 2011年 IgG4-Related Disease — NEJM Review Article from The ...
近日,北京协和医院检验科李永哲教授团队、风湿免疫科张文教授团队在BMC Medicine(IF:11.15,中科院1区)杂志上联合发表IgG4相关疾病(IgG4-related disease,IgG4-RD)的血浆代谢组学研究成果。研究组开展了基于液相色谱-质谱技术的非靶向代谢组学研究,进一步揭示了IgG4-RD的代谢机制,发现了新的可用于诊断及预后评估的潜在...
IgG4相关疾病(IgG4-related disease,IgG4-RD)是一组罕见的、纤维炎性、增生性疾病,常表现为多器官损害,受累器官可包括胰腺、唾液腺、泪腺、垂体、甲状腺、前列腺、乳腺、淋巴结等,其中以胰腺、唾液腺、泪腺损害最为常见。其主要特征是IgG4阳性浆细胞浸润各个受累组织、器官,从而导致其纤维化,同时伴血清IgG4水平升...
IgG4-related disease (IgG4-RD) is increasingly recognised in Western societies as a multi-system, inflammatory, fibrosing disease of unknown aetiology that typically, though not exclusively, presents in older men. The clinical manifestations are diverse and almost any organ may be affected. The car...
当IgG4一RD累及肾脏时即为IgG4相关性肾病(IgG4一related kidney disease,IgG4一RKD),主要包括IgG4相关的小管间质性肾炎(IgG4一related tubulointerstitial He—phritis,IgG4一TIN)和IgG4相关的膜性肾病(IgG4一relatedmembranous nephropathy,IgG4一MN)两个类型。2。,其临床表现多样化,可累及全身多个器官。l临床...
S. Nakamura, T. Ito, K. Notohara, T. Sumida, Y. Tanaka, T. Mimori, T. Chiba, M. Mishima, T. Hibi, H. Tsubouchi, K. Inui, H. Ohara, Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD),...
Our previous studies reveal that CCL18-CCR8 chemokine axis is upregulated in patients of immunoglobulin G4-related disease (IgG4-RD), suggesting that the CCL18–CCR8 axis is implicated in the etiology of IgG4-RD, although whether this axis has a potential as a therapeutic target remains unc...