IgG4-RD具有较大的异质性,根据临床和病理表现可分为增殖型和纤维化型。增殖型主要表现为腺体和上皮组织显著的淋巴浆细胞浸润,纤维化型则腹膜后、硬脑膜、纵隔等部位受累更突出。 IgG4相关性肾脏疾病(IgG4-related kidney disease,IgG4-RKD)表现为IgG4相关性肾小管间质性肾炎(IgG4-related tubulointerstitial nephr...
最后病理诊断:结合免疫组化结果,考虑IgG4相关性涎腺炎并累及周围淋巴结,建议临床结合其它检查进一步诊断。 IgG4相关性疾病(IgG4-related disease)是一种与IgG4相关、可累及多个器官或组织、好发于中老年男性的慢性进行性系统性疾病。 临床表现:该病好发于中老年男性,年龄平均59-68岁,男女之比4-7.5:1。自2001年...
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a fascinating condition recognised as a systemic disease in 2003 [1,2]. The first link between autoimmunity affecting the pancreas, elevated serum IgG4 concentrations and large numbers of IgG4-positive plasma cells in pancreatic tissue was ...
IgG4-related disease (IgG4-RD) is a rare multiorgan condition characterized by three pathology features: lymphoplasmacytic infiltration, storiform fibrosis, and obliterative phlebitis [1]. The hallmark of this condition is the IgG4-positive plasma cell infiltration in affected organs. Various organs...
IgG4相关前列腺炎的低功率视图。前列腺基质表现出致密的炎性浸润和纤维化(H&E,100x) IgG4相关疾病(IgG4-RD),以前称为IgG4相关的全身性疾病,是一种慢性炎症性疾病,其特征是组织浸润淋巴细胞和分泌IgG4的浆细胞,各种程度的纤维化(瘢痕形成)和通常迅速的反应口服...
IgG4-related disease is a systemic fibroinflammatory syndrome of unknown etiology characterized by local inflammatory swelling and tumefactive lesions in one or several organs. It unifies several diseases previously thought to be unrelated. Recently, diagnostic criteria for the disease have been formulated...
IgG4-related disease: a systemic condition with characteristic microscopic features During the first decade of the 21st century, IgG4-related disease (IgG4-RD), a fibroinflammatory condition occurring at multiple sites of the body, has bee... D S?Nke - 《Histology & Histopathology》 被引量:...
IgG4-related disease (IgG4-RD) has only existed as a unique disease entity since 2003, yet remarkable progress has already been achieved in describing the essential features of the disease. A framework for systematic clinical studies has been created by the development of a quantitative disease ...
IgG4-related conditions affecting the digestive tract are part of a multi-organ fibro-inflammatory disorder termed IgG4-related disease (IgG4-RD), with autoimmune pancreatitis and IgG4-related cholangitis being the most prominent manifestations. Gastroin
IgG4-related disease (IgG4-RD) is an increasingly recognised inflammatory and fibrosing condition that commonly shows multisystem involvement. The disease may mimic malignancy and other inflammatory or immune-mediated disorders, but usually has a good response to corticosteroid therapy, underlining the re...