[17]. Lv J, Zhang H, Wong MG, et al. Effect of oral methylprednisolone on clinical outcomes in patients with IgA nephropathy: the testing randomized clinical trial. JAMA, 2017, 318(5): 432-442. [18]. Fellström BC, Barratt J, Cook H, et al. Targeted-release budesonide versus place...
[17]. Lv J, Zhang H, Wong MG, et al. Effect of oral methylprednisolone on clinical outcomes in patients with IgA nephropathy: the testing randomized clinical trial. JAMA, 2017, 318(5): 432-442. [18]. Fellström BC, Barratt J, Cook H, et al. Targeted-release budesonide versus place...
New Drugs Under Evaluation for Treatment of IgA Nephropathy. New drugs are being evaluated for the treatment of IgA nephropathy. These drugs target persistent proteinuria despite months of optimized supportive care. However, it is believed that some of these drugs could be beneficial in managing the...
Targeted-release budesonide versus placebo in patients with IgA nephropathy (NEFIGAN): a double-blind, randomised, placebo-controlled phase 2b trial. Lancet. 2017;389-2117-27. doi:10.1016/S0140-6736(17)30550-0 Travere Therapeutics announces FDA accelerated approval of FILSPARI™ (sparsentan)...
Molecular genetic testing detected an abnormality in FAN1 gene. The heterozygous mutation was present on chromosome 15q13.3. However, IgA nephropathy with KIN is a rare disorder, and its pathogenesis is yet to be clarified.doi:10.1016/j.amjms.2020.04.010Ziliang Wang...
主要缩略词表英文缩写英文全称IgANUGIgAnephropathy,Uterineglobingene中文全称IgA肾病子宫球蛋白基因PCR-RFLPPolymerasechaintreaction聚合酶链反应.限制性ESDRIFNrestrictionfragmentpolymorphismmethodEnd-stagerenaldiseaseinterferon砜tumornecrosisfactoryIL一1Interleukin.1length片段长度多态性法TGF一131Transformationgrowthfactor终末...
Immunoglobulin A (IgA) mediates mucosal responses to food antigens and the intestinal microbiome and is involved in susceptibility to mucosal pathogens, celiac disease, inflammatory bowel disease, and IgA nephropathy. We performed a genome-wide associati
Metrics Abstract IgA Nephropathy (IgAN) is one of the most common causes of chronic kidney damage worldwide. Identifying new genetic factors associated with IgAN risk is of invaluable importance. To explore the association between polymorphisms of IL-23R and IL-17A and the susceptibility of IgAN,...
IgA Nephropathy (IgAN) is the main cause of primary glomerulonephritis, globally. This disease is associated with a wide range of clinical presentations, variable prognosis and a spectrum of histological findings. More than fifty years after its first description, this heterogeneity continues to complic...
Han Chinese Wei Wang1,2,3, Yu Sun4, Yonggui Fu4, Xueqing Yu1,2 and Ming Li1,2 IgA nephropathy is one of the most common glomerulonephritis throughout the world, which is thought to be the multifactorial complex diseases, with genetic and environmental factors contributing to this disease....