IgAReceptorCD89FcαRMesangial cellsImmunoglobulin (Ig)A-nephropathy (IgAN), the most common glomerulonephritis worldwide, is immunohistochemically characterized by the deposition of IgA in the renal mesangium. The mechanism of binding and deposition of IgA in the kidney is still not clear. It has...
IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their surface. A recent Phase II trial revealed that felzartamab, an investigational anti-CD38 monoclonal antibody, helps to reduce proteinuria and maintain patients' kidney function....
Steroid Therapy in IgA Nephropathy: A Retrospective Study in Heavy Proteinuric Cases 29 patients with IgA nephropathy whose proteinuria persisted at a level of 2.0 g/day or more and who received prednisolone treatment for 1–3 years w... Y Kobayashi,K Fujii,Y Hiki,... - 《Nephron》 被引...
Nephritis in Toddlers: This is an inflammation of the kidneys in small children that can be caused by various conditions such as lupus, IgA nephropathy, and other autoimmune diseases. Symptoms may include fever, flank pain, and blood in the urine of toddlers. Hydronephrosis in Children: This is...
In some cases, kidney stones may require surgical removal. From Healthy Resources Understanding Persistent Proteinuria What Is IgA Nephropathy? Find Out Featured Centers What Are the Best PsA Treatments for You? Understanding Biologics 10 Things People With Depression Wish You Knew References Health...
11 NCS can occur concomitant with other conditions such as pregnancy, Henoch-Schönlein purpura, IgA or membranous nephropathy, idiopathic hypercalciuria with urolithiasis, a median arcuate ligament, or May-Thurner syndrome.3 The presentation of NCS in combination with other conditions can confound ...
Preventing and treating kidney disease (nephropathy) in people with hypertensionor diabetes ACE inhibitors also improve survival afterheart attacks. In studies, individuals with hypertension, heart failure, or prior heart attacks who were treated with an ACE inhibitor lived longer than patients who did...
the nephrotic syndrome has seen a growth in its incidence because it has the IGA nephropathy (peripheral form of Henoch Schonlein purpura) as most common cause in the children below 18 years of age. Other causes of nephrotic syndrome like HIV, amyloidosis has also increased in inciden...
What does STOP-IgAN tell us about how to treat IgA nephropathy?doi:10.4997/jrcpe.2016.206S PirachaJ GnanapragasamS M TariqJ R Coll Physicians Edinb
Presents a method of treating IgA nephropathy. Benefits from immunosuppressive treatment; Effects on the downstream processes; Fundamental pathogenic mechanisms.doi:10.1159/000068523JohnFeehallyS. Karger AGNephron Clinical PracticeTreating IgA Nephropathy - Who, When and How?. Feehally John. Nephron. ...