PURPOSE: A biomarker for diagnosing IgA nephropathy is provided to detect IgA nephropathy and early diagnosis and confirm progress. CONSTITUTION: A biomarker composition for diagnosing IgA nephropathy contains at least three or more proteins selected from a protein group of which expression is increased...
The results of future research are eagerly awaited. At present, the most important therapeutic goals in patients with IgA nephropathy are the control of hypertension, the decrease of urinary protein excretion, and the inhibition of progression to end-stage kidney disease. Several investigators have ...
In adults, membranous nephropathy (MN) is a major cause of nephrotic syndrome. However, the etiology of approximately 75% of MN cases is idiopathic. Secondary causes of MN are autoimmune diseases, infection, drugs, and malignancy. The pathogenesis of MN involves formation of immune complex in ...
2.Level of Serum Egf17 and Its Clinical Value as a Novel Diagnostic Biomarker for HCC血清Egf17水平及其作为新的肝细胞癌血清诊断标志物的临床价值 3.Assistance in diagnosis is provided by serology.血清学提供辅助诊断。 4.A new method detecting the aberrant IgA in serum for IgA nephropathy diagonosi...
of 13% in MN patients, demonstrating a trend toward surpassing IgA nephropathy [5]. Research has suggested that in the northeastern region of China, the incidence of IMN has exceeded that of IgA nephropathy, suggesting that IMN is the leading cause of primary glomerulopathies [10,11] and ...
Others, including immunoglobulin A nephropathy The overall prevalence of CD is highly dependent on the HLA DQ2/DQ8 typing and gluten consumption. The population with positive HLA typing for celiac have high chances of developing celiac symptoms when on high gluten consumption. However, the population...
After data calibration, it was found that membranous nephropathy increased 13% annually, and its incidence had a tendency to exceed that of IgA nephropathy [3]. Xu et al analyzed the characteristics of Asian IMN patients and noted that treatment of these patients could not simply follow the ...
Formalin-fixed paraffin-embedded renal biopsy tissues: an underexploited biospecimen resource for gene expression profiling in IgA nephropathy Article Open access 16 September 2020 Landscape of the immune infiltration and identification of molecular diagnostic markers associated with immune cells in patients...
Light-chain cast nephropathy is considered as a MM defining event because it always forms as the result of high monoclonal LC production, indicating a high tumor burden, a situation that requires urgent introduction of chemotherapy.2,3 Although rare, another example is glomerular intracapillary ...
Membranous Nephropathy (MN) is a rare autoimmune cause of kidney failure. Here we report a genome-wide association study (GWAS) for primary MN in 3,782 cases and 9,038 controls of East Asian and European ancestries. We discover two previously unreported